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  2. Cdk14 - cyclin-dependent kinase 14 Gene

Cdk14 - cyclin-dependent kinase 14 Gene

中文名称:细胞周期蛋白依赖性激酶 14

种属: Mus musculus

同用名: Pftk1; mKIAA0834

基因 ID: 18647 | 基因类型: protein coding

关于 Cdk14

Chromosome 5: 4,853,391-5,470,312 reverse strand.GRCm39:CM000998.3

This gene has 15 transcripts (splice variants), 201 orthologues, 25 paralogues and is associated with 2 phenotypes. Biased expression in frontal lobe adult (RPKM 18.7), cortex adult (RPKM 14.) and 13 other tissues.

功能概要

该基因编码的蛋白可启动蛋白激酶活性。预计参与有丝分裂细胞周期相变;蛋白质磷酸化;和规范的 Wnt 信号通路的调控。预计作用于 Wnt 信号通路的上游或内部;细胞分裂;和磷酸化。位于细胞质和细胞核中。以多种结构表达,包括消化系统;中枢神经系统;泌尿生殖系统;呼吸系统;和感觉器官。与人 CDK14(细胞周期蛋白依赖性激酶 14)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables protein kinase activity. Predicted to be involved in mitotic cell cycle phase transition; protein phosphorylation; and regulation of canonical Wnt signaling pathway. Predicted to act upstream of or within Wnt signaling pathway; cell division; and phosphorylation. Located in cytosol and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human CDK14 (cyclin dependent kinase 14). [provided by Alliance of Genome Resources, Apr 2022]

Cdk14 基因产物(2)

mRNA Protein Name
NM_001310448.1 NP_001297377.1 cyclin-dependent kinase 14 isoform 2
NM_011074.3 NP_035204.2 cyclin-dependent kinase 14 isoform 1

Cdk14 蛋白结构

STKc_PFTAIRE1

STKc_PFTAIRE1: cd07869 (128 - 430)

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  • 469 a.a.
蛋白主名 其他名称

cyclin-dependent kinase 14

cell division protein kinase 14

serine/threonine-protein kinase PFTAIRE-1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cdk14 NCBI NCBI:5218