Prkce - protein kinase C, epsilon Gene

中文名称：蛋白激酶 C，ε

种属: Mus musculus

同用名: Pkce; PKC[e]; PKCepsilon; 5830406C15Rik

关于 Prkce

功能概要

该基因编码的蛋白可启动多种功能，包括 14-3-3 蛋白结合活性；肌动蛋白单体结合活性；和钙非依赖性蛋白激酶 C 活性。参与多个过程，包括 TRAM 依赖性 toll 样受体 4 信号通路；肌动蛋白丝聚合的正调控；和成纤维细胞迁移的正调节。作用于多个过程的上游或内部，包括细胞对酒精的反应；细胞通讯的正向调节；和分泌调节。位于几种细胞成分中，包括细胞质；线粒体；和细胞质的核周区。与高尔基体共定位。以多种结构表达，包括中枢神经系统；泌尿生殖系统；心室;神经视网膜;和唾液腺。与人 PRKCE（蛋白激酶 C epsilon）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables several functions, including 14-3-3 protein binding activity; actin monomer binding activity; and calcium-independent protein kinase C activity. Involved in several processes, including TRAM-dependent Toll-like Receptor 4 signaling pathway; positive regulation of actin filament polymerization; and positive regulation of fibroblast migration. Acts upstream of or within several processes, including cellular response to alcohol; positive regulation of cell communication; and regulation of secretion. Located in several cellular components, including cytosol; mitochondrion; and perinuclear region of cytoplasm. Colocalizes with Golgi apparatus. Is expressed in several structures, including central nervous system; genitourinary system; heart ventricle; neural retina; and salivary gland. Orthologous to human PRKCE (protein kinase C epsilon). [provided by Alliance of Genome Resources, Apr 2022]