2. Gene
  3. Ccl21a - chemokine (C-C motif) ligand 21A (serine) Gene

Ccl21a - chemokine (C-C motif) ligand 21A (serine) Gene

  • 基因
  • 蛋白

种属: Mus musculus

同用名: ALP; SLC; plt; CKb9; Tca4; 6Ckine; Gm1987; Scya21; 6CKBAC2; SCYA21a; Scya21b

基因 ID: 18829 | 基因类型: protein coding

关于 Ccl21a

功能概要

Enables CCR7 Chemokine Receptor binding activity and chemokine activity. Involved in several processes, including dendritic cell dendrite assembly; negative regulation of dendritic cell dendrite assembly; and positive regulation of T cell chemotaxis. Acts upstream of or within induction of positive chemotaxis and lymph node development. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in branchial arch; hemolymphoid system; lymph sac; renal vasculature; and trunk. Orthologous to human CCL21 (C-C motif chemokine ligand 21). [provided by Alliance of Genome Resources, Apr 2022]

Ccl21a 基因产物(2)

mRNA Protein Name
NM_011124.4 NP_035254.1 C-C motif chemokine 21a precursor
NM_011124.4 NP_035254.1 C-C motif chemokine 21a precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables CCR7 chemokine receptor binding IPI
IPI: 通过物理相互作用推断
9507024 MGI
enables chemokine activity IDA
IDA: 通过直接分析推断
12200351 MGI
enables chemokine activity IMP
IMP: 通过突变表型推断
27400149 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in T cell costimulation IDA
IDA: 通过直接分析推断
15845453 MGI
involved in cell maturation IDA
IDA: 通过直接分析推断
15845453 MGI
involved in cellular response to chemokine IMP
IMP: 通过突变表型推断
27400149 MGI
involved in chemokine (C-C motif) ligand 21 signaling pathway IMP
IMP: 通过突变表型推断
27400149 MGI
involved in dendritic cell chemotaxis IDA
IDA: 通过直接分析推断
12200351 MGI
involved in dendritic cell dendrite assembly IDA
IDA: 通过直接分析推断
12200351 MGI
involved in immunological synapse formation IDA
IDA: 通过直接分析推断
15845453 MGI
acts upstream of or within induction of positive chemotaxis IDA
IDA: 通过直接分析推断
9548511 MGI
acts upstream of or within lymph node development IMP
IMP: 通过突变表型推断
12732660 MGI
involved in negative regulation of dendritic cell dendrite assembly IDA
IDA: 通过直接分析推断
12200351 MGI
involved in positive regulation of T cell chemotaxis IMP
IMP: 通过突变表型推断
27400149 MGI
involved in positive regulation of chemotaxis IDA
IDA: 通过直接分析推断
9507024 MGI
involved in positive regulation of dendritic cell antigen processing and presentation IDA
IDA: 通过直接分析推断
15845453 MGI
involved in positive regulation of glycoprotein biosynthetic process IDA
IDA: 通过直接分析推断
15845453 MGI
involved in positive regulation of receptor-mediated endocytosis IDA
IDA: 通过直接分析推断
12609829 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

C-C motif chemokine 21a

CC chemokine 6Ckine-ser

CCL21-Ser

beta-chemokine exodus-2

exodus-2

small inducible cytokine A21a

thymus-derived chemotactic agent 4

重组 Ccl21a 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72756 6Ckine/CCL21A Protein, Mouse P84444 (S24-G133) ≥95%
HY-P75545 6Ckine/CCL21A Protein, Mouse (sf9, His) P84444 (S24-G133) ≥95%
HY-P75546 6Ckine/CCL21A Protein, Mouse (sf9) P84444 (S24-G133) ≥95%
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