1. Gene
  2. Ctsa - cathepsin A Gene

Ctsa - cathepsin A Gene

种属: Mus musculus

同用名: PPCA; Ppgb

基因 ID: 19025 | 基因类型: protein coding

关于 Ctsa

功能概要

This gene encodes a glycoprotein with deamidase, esterase and Carboxypeptidase activities. The encoded protein associates with and provides a protective function to the lysosomal Enzymes beta-galactosidase and neuraminidase. Deficiency of the related gene in humans results in galactosialidosis. The proprotein is processed into two shorter chains. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013]

Ctsa 基因产物(2)

mRNA Protein Name
NM_001038492.2 NP_001033581.1 lysosomal protective protein isoform b preproprotein
NM_008906.4 NP_032932.2 lysosomal protective protein isoform a preproprotein
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
9425240 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of chaperone-mediated autophagy IMP
IMP: 通过突变表型推断
12505983 MGI
involved in regulation of protein stability IMP
IMP: 通过突变表型推断
12505983 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

lysosomal protective protein

carboxypeptidase C

carboxypeptidase L

protective protein cathepsin A

protective protein for beta-galactosidase

重组 Ctsa 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74346 Cathepsin A Protein, Mouse (HEK293, His) P16675 (A24-Y474) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ctsa NCBI NCBI:5476