2. Gene
  3. Ppt1 - palmitoyl-protein thioesterase 1 Gene

Ppt1 - palmitoyl-protein thioesterase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: PPT; CLN1; INCL; D4Ertd184e; 9530043G02Rik

基因 ID: 19063 | 基因类型: protein coding

关于 Ppt1

功能概要

Enables palmitoyl-(protein) hydrolase activity. Acts upstream of or within several processes, including grooming behavior; protein catabolic process; and regulation of Phospholipase A2 activity. Located in several cellular components, including dendrite; lysosome; and neuronal cell body. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Used to study neuronal ceroid lipofuscinosis 1 and neuronal ceroid lipofuscinosis 3. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 1. Orthologous to human PPT1 (palmitoyl-protein thioesterase 1). [provided by Alliance of Genome Resources, Apr 2022]

Ppt1 基因产物(1)

mRNA Protein Name
NM_008917.3 NP_032943.2 palmitoyl-protein thioesterase 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables palmitoyl-(protein) hydrolase activity IDA
IDA: 通过直接分析推断
12483688 MGI
enables palmitoyl-(protein) hydrolase activity IMP
IMP: 通过突变表型推断
11717424 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
19941651 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within adult locomotory behavior IMP
IMP: 通过突变表型推断
11717424 MGI
acts upstream of or within associative learning IMP
IMP: 通过突变表型推断
15885820 MGI
acts upstream of or within grooming behavior IMP
IMP: 通过突变表型推断
11717424 MGI
acts upstream of or within lysosome organization IMP
IMP: 通过突变表型推断
16368712 MGI
acts upstream of or within macromolecule catabolic process IMP
IMP: 通过突变表型推断
15647513 MGI
acts upstream of or within neurotransmitter secretion IMP
IMP: 通过突变表型推断
16242638 MGI
acts upstream of or within protein catabolic process IMP
IMP: 通过突变表型推断
16368712 MGI
acts upstream of or within protein depalmitoylation IMP
IMP: 通过突变表型推断
11717424 MGI
acts upstream of or within regulation of phospholipase A2 activity IMP
IMP: 通过突变表型推断
17341491 MGI
acts upstream of or within visual perception IMP
IMP: 通过突变表型推断
15649713 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
12483688 MGI
located in dendrite IDA
IDA: 通过直接分析推断
10611498 MGI
located in extracellular space IDA
IDA: 通过直接分析推断
9685319 MGI
located in lysosome IDA
IDA: 通过直接分析推断
9685319 MGI
located in lysosome IMP
IMP: 通过突变表型推断
16242638 MGI
located in neuronal cell body IDA
IDA: 通过直接分析推断
10611498 MGI
is active in presynaptic cytosol IDA
IDA: 通过直接分析推断
35358180 MGI
is active in presynaptic cytosol IEP
IEP: 通过表达模式推断
35358180 MGI
is active in synaptic vesicle membrane IDA
IDA: 通过直接分析推断
18704195 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

palmitoyl-protein thioesterase 1

PPT-1

palmitoyl-protein hydrolase 1

重组 Ppt1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P700622 PPT1 Protein, Mouse (HEK293, His) O88531 (D28-K306) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-111621 DC661 99.53% 否
HY-120252 ABC44 Inhibitor 98.7% 否
HY-170670 DQ661 Inhibitor / 否
HY-RS11038 PPT1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ppt1 NCBI NCBI:5538
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