2. Gene
  3. Prlr - prolactin receptor Gene

Prlr - prolactin receptor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Pr-1; Pr-3; Prlr-rs1

基因 ID: 19116 | 基因类型: protein coding

关于 Prlr

功能概要

Enables Prolactin receptor activity. Involved in positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including gland development; receptor signaling pathway via JAK-STAT; and response to bacterium. Predicted to be located in cell surface. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system gland; and limb segment. Used to study familial medullary thyroid carcinoma. Human ortholog(s) of this gene implicated in hyperprolactinemia. Orthologous to human PRLR (Prolactin receptor). [provided by Alliance of Genome Resources, Apr 2022]

Prlr 基因产物(6)

mRNA Protein Name
NM_001253781.1 NP_001240710.1 prolactin receptor isoform 2 precursor
NM_001253782.2 NP_001240711.1 prolactin receptor isoform 3 precursor
NM_011169.5 NP_035299.4 prolactin receptor isoform 1 precursor
NM_001253781.1 NP_001240710.1 prolactin receptor isoform 2 precursor
NM_001253782.2 NP_001240711.1 prolactin receptor isoform 3 precursor
NM_011169.5 NP_035299.4 prolactin receptor isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables prolactin receptor activity IDA
IDA: 通过直接分析推断
6303755 MGI
enables prolactin receptor activity IMP
IMP: 通过突变表型推断
11706048 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
20075866 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cell surface receptor signaling pathway via JAK-STAT IMP
IMP: 通过突变表型推断
16469767 MGI
acts upstream of or within lactation IGI
IGI: 通过遗传相互作用推断
11445538 MGI
acts upstream of or within lactation IMP
IMP: 通过突变表型推断
11706048 MGI
acts upstream of or within mammary gland alveolus development IGI
IGI: 通过遗传相互作用推断
11445538 MGI
acts upstream of or within mammary gland alveolus development IMP
IMP: 通过突变表型推断
16469767 MGI
acts upstream of or within mammary gland epithelial cell differentiation IGI
IGI: 通过遗传相互作用推断
16469767 MGI
acts upstream of or within mammary gland epithelium development IMP
IMP: 通过突变表型推断
12040017 MGI
involved in positive regulation of cold-induced thermogenesis IMP
IMP: 通过突变表型推断
18253483 MGI
acts upstream of or within prostate gland growth IMP
IMP: 通过突变表型推断
12810576 MGI
acts upstream of or within regulation of cell adhesion IMP
IMP: 通过突变表型推断
11706048 MGI
acts upstream of or within regulation of epithelial cell differentiation IMP
IMP: 通过突变表型推断
11706048 MGI
acts upstream of or within response to bacterium IEP
IEP: 通过表达模式推断
23012479 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

prolactin receptor

PRL-R

prolactin receptor related sequence 1

重组 Prlr 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71235 Prolactin R Protein, Mouse (210a.a, HEK293, His) Q08501 (Q20-D229) ≥95%
HY-P73694 Prolactin R Protein, Mouse (HEK293, His-Fc) Q08501 (Q20-D229) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11163 PRLR Human Pre-designed siRNA Set A Pre-designed Sets / 否
抗体抑制剂 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P99238 Rolinsatamab 97.16% 否
HY-P99881 Rolinsatamab talirine / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Prlr NCBI NCBI:5618
Canis familiaris Prlr NCBI NCBI:479363
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