1. 重组蛋白
  2. Receptor Proteins
  3. Prolactin R 蛋白, Mouse (210a.a, HEK293, His)

Prolactin R 蛋白, Mouse (210a.a, HEK293, His)

目录号: HY-P71235
COA 产品使用指南

催乳素 R 蛋白是垂体前叶激素催乳素的受体,并与 SMARCA1、NEK3 和 VAV2 显着相互作用。后两种相互作用是催乳素依赖性的,强调受体在转导催乳素诱导的信号中的作用,这些信号对于多种生理过程,特别是在生殖和哺乳中至关重要。Prolactin R 蛋白, Mouse (210a.a, HEK293, His) 是重组的 催乳素 R 蛋白,由 HEK293 表达,带有 C-6*His 标签。

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规格 价格 是否有货 数量
10 μg ¥780 In-stock
50 μg ¥2200 In-stock
100 μg ¥3750 询价
> 100 μg   询价  

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  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

Prolactin R protein serves as a receptor for the anterior pituitary hormone prolactin and significantly interacts with SMARCA1, NEK3, and VAV2.The latter two interactions are prolactin-dependent, emphasizing the role of the receptor in transducing prolactin-induced signals that are critical for multiple physiological processes, particularly in reproduction and lactation.Prolactin R Protein, Mouse (HEK293, His) is the recombinant mouse-derived Prolactin R protein, expressed by HEK293 , with C-6*His labeled tag.

研究背景

催乳素 R 蛋白是垂体前叶激素催乳素的受体。它与 SMARCA1、NEK3 和 VAV2 进行重要的相互作用,后两种相互作用是催乳素依赖性的。这些分子关联强调了受体在转导催乳素触发的信号中的作用,催乳素是各种生理过程的核心激素,特别是与生殖和哺乳相关的生理过程。与 SMARCA1、NEK3 和 VAV2 的相互作用凸显了以催乳素依赖性方式协调细胞反应的复杂调控网络。

种属

Mouse

表达系统

HEK293

标签

C-6*His

蛋白编号

Q08501 (Q20-D229)

基因 ID
蛋白结构
N-term
Prolactin R (Q20-D229)
Accession # Q08501
6*His
C-term
同用名
Prolactin receptor; PRL-R; Prlr; Prolactin R; PRLR
氨基酸序列

QSPPGKPEIHKCRSPDKETFTCWWNPGSDGGLPTNYSLTYSKEGEKNTYECPDYKTSGPNSCFFSKQYTSIWKIYIITVNATNEMGSSTSDPLYVDVTYIVEPEPPRNLTLEVKQLKDKKTYLWVKWLPPTITDVKTGWFTMEYEIRLKSEEADEWEIHFTGHQTQFKVFDLYPGQKYLVQTRCKPDHGYWSRWGQEKSIEIPNDFTLKD

分子量

33-40 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

性状

无菌粉末

组分

Lyophilized from a 0.2 μm filtered solution of 20 mM Cirate, 6% Sucrose, 4% Dextran-70, 50 mM NaCl, 0.05% Tween80, pH 3.5.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料

Prolactin R Protein, Mouse (210a.a, HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
Prolactin R Protein, Mouse (210a.a, HEK293, His)
目录号:
HY-P71235
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