1. Gene
  2. Rspo1 - R-spondin 1 Gene

Rspo1 - R-spondin 1 Gene

种属: Mus musculus

同用名: Rspondin; R-spondin

基因 ID: 192199 | 基因类型: protein coding

关于 Rspo1

功能概要

Enables heparin binding activity and signaling receptor binding activity. Involved in positive regulation of canonical Wnt signaling pathway. Acts upstream of or within several processes, including male meiotic nuclear division; positive regulation of non-canonical Wnt signaling pathway; and regulation of male germ cell proliferation. Located in extracellular space and nucleus. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and skeleton. Orthologous to human RSPO1 (R-spondin 1). [provided by Alliance of Genome Resources, Apr 2022]

Rspo1 基因产物(1)

mRNA Protein Name
NM_138683.2 NP_619624.2 R-spondin-1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables heparin binding IDA
IDA: 通过直接分析推断
16543246 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
21693646 MGI
enables signaling receptor binding IPI
IPI: 通过物理相互作用推断
16543246 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
14732490 MGI
located in nucleus IDA
IDA: 通过直接分析推断
14732490 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

R-spondin-1

R-spondin homolog

cristin-3

cysteine-rich and single thrombospondin domain-containing protein 3

mCristin-3

roof plate-specific spondin-1

thrombospondin type 1 domain containing gene Rspondin

重组 Rspo1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76012 RSPO1/R-spondin-1 Protein, Mouse (CHO, His) Q9Z132/NP_619624.2 (S21-Q265) ≥95%
HY-P78344 RSPO1/R-spondin-1 Protein, Mouse (HEK293, His) Q9Z132 (S21-Q265) ≥95%
HY-P700255 RSPO1/R-spondin-1 Protein, Mouse (189aa, His) Q9Z132 (S21-G209) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rspo1 NCBI NCBI:284654