2. Gene
  3. EEF1B2 - eukaryotic translation elongation factor 1 beta 2 Gene

EEF1B2 - eukaryotic translation elongation factor 1 beta 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：真核翻译延伸因子 1 beta 2

种属: Homo sapiens

同用名: EF1B; EEF1B; EEF1B1

基因 ID: 1933 | 基因类型: protein coding

关于 EEF1B2

Cytogenetic location: 2q33.3 Genomic coordinates (GRCh38): 2:206,159,609-206,162,928 (from NCBI)

This gene has 11 transcripts (splice variants), 1 gene allele, 182 orthologues, 2 paralogues and is associated with 1 phenotype. Ubiquitous expression in bone marrow (RPKM 282.5), lymph node (RPKM 249.8) and 25 other tissues.

功能概要

该基因编码翻译延伸因子。该蛋白质是一种鸟嘌呤核苷酸交换因子，参与氨酰化 tRNA 向核糖体的转移。可变剪接导致三种转录本变体，它们仅在 5' UTR 上有所不同。[RefSeq 提供，2008 年 7 月]

This gene encodes a translation elongation factor. The protein is a guanine nucleotide exchange factor involved in the transfer of aminoacylated tRNAs to the ribosome. Alternative splicing results in three transcript variants which differ only in the 5' UTR. [provided by RefSeq, Jul 2008]

EEF1B2 基因产物(3)

mRNA Protein Name
NM_001037663.2 NP_001032752.1 elongation factor 1-beta
NM_001959.4 NP_001950.1 elongation factor 1-beta
NM_021121.4 NP_066944.1 elongation factor 1-beta
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16169070 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
8743958 GOA
colocalizes with endoplasmic reticulum IDA
IDA: 通过直接分析推断
8743958 GOA
NOT located in nucleus IDA
IDA: 通过直接分析推断
12426392 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

EEF1B2 蛋白结构

EF-1_beta_acid

EF-1_beta_acid: Eukaryotic elongation factor 1 beta central acidic region (103 - 130)

EF1_GNE

EF1_GNE: EF-1 guanine nucleotide exchange domain (139 - 225)

  • 0
  • 100
  • 200
  • 225 a.a.
蛋白主名 其他名称

elongation factor 1-beta

EF-1-beta

重组 EEF1B2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76898 EEF1B2 Protein, Human (His) P24534 (G2-I225) ≥95%

关联疾病

疾病名称 别名
Cystic Echinococcosis

Echinococcus Granulosus Infection

Echinococcus Granulosus Infection Of Lung

Echinococcus Granulosus

Echinococcus Granulosus Infection Of Thyroid

Echinococcus Granulosus Infectious Disease

Echinococcus Granulosus Infectious Disease Of Liver

Echinococcus Granulosus Infectious Disease Of Thyroid

Liver Echinococcus Granulosus

Lung Echinococcus Granulosus

Thyroid Echinococcus Granulosus

Unilocular Echinococcosis

Unilocular Hydatid Disease

Hydatid Disease

Hydatidosis

Echinococcosis
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04176 EEF1B2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus EEF1B2 MGD MGI:1929520
Macaca mulatta EEF1B2 VGNC VGNC:104523
Rattus norvegicus EEF1B2 RGD RGD:1311415
Bos taurus EEF1B2 VGNC VGNC:54422
Felis catus EEF1B2 VGNC VGNC:82529
Canis familiaris EEF1B2 VGNC VGNC:57381
Others EEF1B2 NCBI
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