2. Gene
  3. Rbp4 - retinol binding protein 4, plasma Gene

Rbp4 - retinol binding protein 4, plasma Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Rbp-4

基因 ID: 19662 | 基因类型: protein coding

关于 Rbp4

功能概要

Enables retinol binding activity. Involved in several processes, including animal organ development; gluconeogenesis; and negative regulation of cardiac muscle cell proliferation. Acts upstream of or within several processes, including detection of light stimulus involved in visual perception; retinoid metabolic process; and terpenoid transport. Located in extracellular space. Is expressed in several structures, including adipose tissue; brain; genitourinary system; gut; and hindlimb. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human RBP4 (retinol binding protein 4). [provided by Alliance of Genome Resources, Apr 2022]

Rbp4 基因产物(2)

mRNA Protein Name
NM_001159487.1 NP_001152959.1 retinol-binding protein 4 isoform 1
NM_011255.3 NP_035385.1 retinol-binding protein 4 isoform 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
23105095 MGI
enables retinol binding IDA
IDA: 通过直接分析推断
12484775 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cardiac muscle tissue development IMP
IMP: 通过突变表型推断
12663486 MGI
acts upstream of or within detection of light stimulus involved in visual perception IMP
IMP: 通过突变表型推断
12484775 MGI
acts upstream of or within embryo development IGI
IGI: 通过遗传相互作用推断
18093970 MGI
involved in embryonic organ morphogenesis IMP
IMP: 通过突变表型推断
15994349 MGI
involved in embryonic retina morphogenesis in camera-type eye IMP
IMP: 通过突变表型推断
10469643 MGI
involved in embryonic skeletal system development IMP
IMP: 通过突变表型推断
15994349 MGI
involved in eye development IMP
IMP: 通过突变表型推断
15994349 MGI
involved in female genitalia morphogenesis IMP
IMP: 通过突变表型推断
15994349 MGI
involved in gluconeogenesis IMP
IMP: 通过突变表型推断
16034410 MGI
involved in heart development IMP
IMP: 通过突变表型推断
15994349 MGI
involved in heart trabecula formation IMP
IMP: 通过突变表型推断
12663486 MGI
involved in lung development IMP
IMP: 通过突变表型推断
15994349 MGI
acts upstream of or within male gonad development IMP
IMP: 通过突变表型推断
16586441 MGI
involved in negative regulation of cardiac muscle cell proliferation IMP
IMP: 通过突变表型推断
12663486 MGI
involved in positive regulation of immunoglobulin production IDA
IDA: 通过直接分析推断
10944490 MGI
acts upstream of or within response to insulin IMP
IMP: 通过突变表型推断
16034410 MGI
acts upstream of or within retina development in camera-type eye IMP
IMP: 通过突变表型推断
11562477 MGI
acts upstream of or within retinal metabolic process IMP
IMP: 通过突变表型推断
11562477 MGI
acts upstream of or within retinol metabolic process IGI
IGI: 通过遗传相互作用推断
18093970 MGI
acts upstream of or within retinol transport IGI
IGI: 通过遗传相互作用推断
23105095 MGI
acts upstream of or within retinol transport IMP
IMP: 通过突变表型推断
11562477 MGI
acts upstream of or within spermatogenesis IMP
IMP: 通过突变表型推断
16586441 MGI
involved in urinary bladder development IMP
IMP: 通过突变表型推断
15994349 MGI
involved in uterus development IMP
IMP: 通过突变表型推断
15994349 MGI
involved in vagina development IMP
IMP: 通过突变表型推断
15994349 MGI
acts upstream of or within vitamin A import into cell IMP
IMP: 通过突变表型推断
12484775 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
16034410 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

retinol-binding protein 4

PRBP

RBP

plasma retinol-binding protein

retinol binding protein 4, cellular

重组 Rbp4 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74599 RBP4 Protein, Mouse (HEK293, His) Q00724 (E19-L201) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-107633 A 1120 99.42% 否
HY-143793 RBP4 inhibitor 1 Inhibitor 99.74% 否
HY-147366 RBP4 ligand-1 Inhibitor / 否
HY-RS11769 RBP4 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rbp4 NCBI NCBI:5950
Canis familiaris Rbp4 NCBI NCBI:477775
Macaca fascicularis Rbp4 NCBI NCBI:102136826
Rattus norvegicus Rbp4 NCBI NCBI:25703
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