FCSK - fucose kinase Gene

中文名称：岩藻糖激酶

种属: Homo sapiens

同用名: FUK; CDGF2; 1110046B12Rik

关于 FCSK

功能概要

该基因编码的蛋白质属于 GHMP (半乳糖、高丝氨酸、甲羟戊酸和磷酸甲羟戊酸) 激酶家族，催化 L-岩藻糖磷酸化形成 β-L-岩藻糖 1-磷酸。该酶催化在糖蛋白和糖脂合成中利用游离 L-岩藻糖的第一步。 L-岩藻糖可能在介导许多细胞间相互作用方面很重要，例如血型抗原识别、炎症和转移。虽然该基因可能存在多个转录变体，但迄今为止仅描述了一个的全长性质。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene belongs to the GHMP (galacto-, homoserine, mevalonate and phosphomevalonate) kinase family and catalyzes the phosphorylation of L-fucose to form beta-L-fucose 1-phosphate. This Enzyme catalyzes the first step in the utilization of free L-fucose in glycoprotein and glycolipid synthesis. L-fucose may be important in mediating a number of cell-cell interactions such as blood group antigen recognition, inflammation, and metastatis. While several transcript variants may exist for this gene, the full-length nature of only one has been described to date. [provided by RefSeq, Jul 2008]