2. Gene
  3. Rps6ka2 - ribosomal protein S6 kinase, polypeptide 2 Gene

Rps6ka2 - ribosomal protein S6 kinase, polypeptide 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：核糖体蛋白 S6 激酶，多肽 2

种属: Mus musculus

同用名: Rsk3; 90kDa; p90rsk; pp90rsk; D17Wsu134e; Rps6ka-rs1

基因 ID: 20112 | 基因类型: protein coding

关于 Rps6ka2

Chromosome 17: 7,437,514-7,570,714 forward strand.GRCm39:CM001010.3

This gene has 5 transcripts (splice variants), 209 orthologues, 7 paralogues and is associated with 3 phenotypes. Ubiquitous expression in ovary adult (RPKM 18.1), heart adult (RPKM 11.1) and 25 other tissues.

功能概要

该基因编码的蛋白可启动核糖体蛋白 S6 激酶活性。作用于多个过程的上游或内部，包括心肌细胞凋亡过程；卵母细胞成熟；和基因表达的调控。位于细胞质和减数分裂纺锤体中。以多种结构表达，包括消化系统；早孕;泌尿生殖系统；神经系统;和感觉器官。与人 RPS6KA2（核糖体蛋白 S6 激酶 A2）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables ribosomal protein S6 kinase activity. Acts upstream of or within several processes, including cardiac muscle cell apoptotic process; oocyte maturation; and regulation of gene expression. Located in cytoplasm and meiotic spindle. Is expressed in several structures, including alimentary system; early conceptus; genitourinary system; nervous system; and sensory organ. Orthologous to human RPS6KA2 (ribosomal protein S6 kinase A2). [provided by Alliance of Genome Resources, Apr 2022]

Rps6ka2 基因产物(2)

mRNA Protein Name
NM_011299.4 NP_035429.1 ribosomal protein S6 kinase alpha-2
NM_011299.4 NP_035429.1 ribosomal protein S6 kinase alpha-2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15526037 MGI
enables protein kinase activity IDA
IDA: 通过直接分析推断
15526037 MGI
enables protein serine/threonine kinase activity IDA
IDA: 通过直接分析推断
7508917 MGI
enables ribosomal protein S6 kinase activity IDA
IDA: 通过直接分析推断
16585392 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within brain renin-angiotensin system IDA
IDA: 通过直接分析推断
16585392 MGI
acts upstream of or within cardiac muscle cell apoptotic process IDA
IDA: 通过直接分析推断
16585392 MGI
acts upstream of or within cellular response to carbohydrate stimulus IDA
IDA: 通过直接分析推断
16585392 MGI
acts upstream of or within heart contraction IDA
IDA: 通过直接分析推断
16585392 MGI
acts upstream of or within heart development IDA
IDA: 通过直接分析推断
16585392 MGI
acts upstream of or within negative regulation of meiotic nuclear division IDA
IDA: 通过直接分析推断
15526037 MGI
acts upstream of or within oocyte maturation IDA
IDA: 通过直接分析推断
15526037 MGI
acts upstream of or within peptidyl-serine phosphorylation IDA
IDA: 通过直接分析推断
7508917 MGI
acts upstream of or within positive regulation of gene expression IDA
IDA: 通过直接分析推断
16585392 MGI
acts upstream of or within protein phosphorylation IDA
IDA: 通过直接分析推断
15526037 MGI
acts upstream of or within regulation of protein processing IMP
IMP: 通过突变表型推断
16585392 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
15526037 MGI
located in meiotic spindle IDA
IDA: 通过直接分析推断
15526037 MGI
located in spindle IDA
IDA: 通过直接分析推断
15509711 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

Rps6ka2 蛋白结构

STKc_RSK_N

STKc_RSK_N: cd05582 (62 - 378)

STKc_RSK3_C

STKc_RSK3_C: cd14178 (410 - 702)

  • 0
  • 200
  • 400
  • 600
  • 733 a.a.
蛋白主名 其他名称

ribosomal protein S6 kinase alpha-2

90 kDa ribosomal protein S6 kinase 2

MAP kinase-activated protein kinase 1c

MAPK-activated protein kinase 1c

MAPKAP kinase 1c

MAPKAPK-1c

RSK-3

S6K-alpha 2

p90-RSK 2

p90RSK2

pp90RSK3

protein-tyrosine kinase Mpk-9

ribosomal S6 kinase 3

ribosomal protein S6 kinase, 90kD, polypeptide 2

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12251 RPS6KA2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS12252 Rps6ka2 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS12253 Rps6ka2 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rps6ka2 NCBI NCBI:6196
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