1. Gene
  2. Selp - selectin, platelet Gene

Selp - selectin, platelet Gene

种属: Mus musculus

同用名: Grmp; CD62P; LECAM3; PADGEM; GMP-140

基因 ID: 20344 | 基因类型: protein coding

关于 Selp

功能概要

Enables calcium-dependent protein binding activity and sialic acid binding activity. Involved in positive regulation of leukocyte tethering or rolling and positive regulation of platelet activation. Acts upstream of or within several processes, including heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; leukocyte tethering or rolling; and positive regulation of leukocyte migration. Located in external side of plasma membrane. Is expressed in blood and liver. Human ortholog(s) of this gene implicated in atopic dermatitis and myocardial infarction. Orthologous to human SELP (Selectin P). [provided by Alliance of Genome Resources, Apr 2022]

Selp 基因产物(1)

mRNA Protein Name
NM_011347.2 NP_035477.1 P-selectin precursor
蛋白主名 其他名称

P-selectin

CD62 antigen-like family member P

granule membrane protein 140

leukocyte-endothelial cell adhesion molecule 3

platelet activation dependent granule-external membrane protein

重组 Selp 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72408 P-selectin Protein, Mouse (Biotinylated, HEK293, Avi-His) Q01102 (W42-A709) ≥95%
HY-P73383 P-Selectin Protein, Mouse (HEK293, Fc) Q01102 (W42-A709) ≥95%
HY-P78349 P-Selectin Protein, Mouse (HEK293, His) Q01102 (W42-A709) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Selp NCBI NCBI:6403
Macaca fascicularis Selp NCBI NCBI:102141875
Rattus norvegicus Selp NCBI NCBI:25651
Macaca mulatta Selp NCBI NCBI:701277