2. Gene
  3. Selp - selectin P Gene

Selp - selectin P Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: PSELECT

基因 ID: 25651 | 基因类型: protein coding

关于 Selp

功能概要

Predicted to enable several functions, including fucose binding activity; heparin binding activity; and lipopolysaccharide binding activity. Involved in several processes, including leukocyte migration; regulation of cellular extravasation; and response to lipopolysaccharide. Located in external side of plasma membrane and extracellular space. Used to study acute necrotizing pancreatitis and anti-basement membrane glomerulonephritis. Biomarker of atherosclerosis; colitis; congestive heart failure; and myocardial infarction. Human ortholog(s) of this gene implicated in atopic dermatitis and myocardial infarction. Orthologous to human SELP (Selectin P). [provided by Alliance of Genome Resources, Apr 2022]

Selp 基因产物(1)

mRNA Protein Name
NM_013114.2 NP_037246.2 P-selectin precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell-cell adhesion IMP
IMP: 通过突变表型推断
14963004 RGD
involved in leukocyte migration IMP
IMP: 通过突变表型推断
12377736 RGD
involved in positive regulation of cell adhesion IMP
IMP: 通过突变表型推断
19451746 RGD
involved in regulation of cellular extravasation IMP
IMP: 通过突变表型推断
12081568 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
7520013 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
18095572 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
14963004 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
18471420 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

P-selectin

CD62 antigen-like family member P

GMP-140

LECAM3

PADGEM

granule membrane protein 140

leukocyte-endothelial cell adhesion molecule 3

platelet activation dependent granule-external membrane protein

selectin, platelet

重组 Selp 蛋白

目录号 产品名 蛋白编号 纯度
HY-P73385 P-Selectin Protein, Rat (HEK293, Fc) P98106/AAI01920.1 (W42-Q700) ≥95%
HY-P73689 P-Selectin Protein, Rat (HEK293, His) P98106/AAI01920.1 (W42-Q700) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12647 SELP Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Selp NCBI NCBI:6403
Macaca fascicularis Selp NCBI NCBI:102141875
Mus musculus Selp NCBI NCBI:20344
Macaca mulatta Selp NCBI NCBI:701277
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