1. Gene
  2. St6gal1 - beta galactoside alpha 2,6 sialyltransferase 1 Gene

St6gal1 - beta galactoside alpha 2,6 sialyltransferase 1 Gene

种属: Mus musculus

同用名: Siat1; St6gal; St6galI; St6Gal-I

基因 ID: 20440 | 基因类型: protein coding

关于 St6gal1

功能概要

This gene encodes a member of Glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on chromosome 15. [provided by RefSeq, Nov 2011]

St6gal1 基因产物(3)

mRNA Protein Name
NM_001252505.1 NP_001239434.1 beta-galactoside alpha-2,6-sialyltransferase 1
NM_001252506.1 NP_001239435.1 beta-galactoside alpha-2,6-sialyltransferase 1
NM_145933.4 NP_666045.1 beta-galactoside alpha-2,6-sialyltransferase 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables beta-galactoside alpha-2,6-sialyltransferase activity IDA
IDA: 通过直接分析推断
22039275 MGI
enables beta-galactoside alpha-2,6-sialyltransferase activity IMP
IMP: 通过突变表型推断
12068010 MGI
enables sialyltransferase activity IDA
IDA: 通过直接分析推断
12966079 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in protein N-linked glycosylation via asparagine IDA
IDA: 通过直接分析推断
22039275 MGI
acts upstream of or within protein glycosylation IMP
IMP: 通过突变表型推断
12068010 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

beta-galactoside alpha-2,6-sialyltransferase 1

CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1

ST6Gal I

alpha 2,6-ST 1

重组 St6gal1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76094 ST6GAL1 Protein, Mouse (HEK293, His) Q64685 (K27-C403) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens St6gal1 NCBI NCBI:6480
Rattus norvegicus St6gal1 NCBI NCBI:25197