2. Gene
  3. STX2 - syntaxin 2 Gene

STX2 - syntaxin 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：突触蛋白 2

种属: Homo sapiens

同用名: EPM; EPIM; STX2A; STX2B; STX2C

基因 ID: 2054 | 基因类型: protein coding

关于 STX2

Cytogenetic location: 12q24.33 Genomic coordinates (GRCh38): 12:130,789,600-130,839,250 (from NCBI)

This gene has 13 transcripts (splice variants), 254 orthologues and 12 paralogues. Ubiquitous expression in testis (RPKM 4.3), lung (RPKM 3.9) and 25 other tissues.

功能概要

该基因的产物属于突触融合蛋白/epimorphin 蛋白家族。 syntaxins 是一个大的蛋白质家族，涉及细胞内运输囊泡的靶向和融合。该基因的产物调节上皮间充质相互作用和上皮细胞形态发生和激活。已经鉴定出编码不同亚型的选择性剪接转录物变体。[RefSeq 提供，2008 年 7 月]

The product of this gene belongs to the syntaxin/epimorphin family of proteins. The syntaxins are a large protein family implicated in the targeting and fusion of intracellular transport vesicles. The product of this gene regulates epithelial-mesenchymal interactions and epithelial cell morphogenesis and activation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

STX2 基因产物(9)

mRNA Protein Name
NM_001351049.2 NP_001337978.2 syntaxin-2 isoform 3
NM_001351050.2 NP_001337979.1 syntaxin-2 isoform 4
NM_001351051.2 NP_001337980.1 syntaxin-2 isoform 5
NM_001351052.2 NP_001337981.1 syntaxin-2 isoform 6
NM_001413773.1 NP_001400702.1 syntaxin-2 isoform 7
NM_001413774.1 NP_001400703.1 syntaxin-2 isoform 8
NM_001413775.1 NP_001400704.1 syntaxin-2 isoform 2
NM_001980.5 NP_001971.2 syntaxin-2 isoform 1
NM_194356.4 NP_919337.1 syntaxin-2 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
12773094 GOA
enables structural molecule activity IDA
IDA: 通过直接分析推断
22226963 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to oxidative stress IDA
IDA: 通过直接分析推断
22226963 GOA
involved in cornified envelope assembly IDA
IDA: 通过直接分析推断
22226963 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in basolateral plasma membrane IDA
IDA: 通过直接分析推断
16339081 GOA
located in extracellular space IDA
IDA: 通过直接分析推断
22226963 GOA
located in lamellipodium IDA
IDA: 通过直接分析推断
21720706 GOA
located in plasma membrane IDA
IDA: 通过直接分析推断
21720706 GOA
part of protein-containing complex IDA
IDA: 通过直接分析推断
22226963 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

STX2 蛋白结构

Syntaxin

Syntaxin: Syntaxin (28 - 130)

SNARE

SNARE: SNARE domain (197 - 258)

  • 0
  • 100
  • 200
  • 288 a.a.
蛋白主名 其他名称

syntaxin-2

epimorphin

关联疾病

疾病名称 别名
Acute Diarrhea
Dysentery

Infectious Diarrhea
Campylobacteriosis

Campylobacter Infections

Campylobacter Infection

Enteric Campylobacteriosis
Shigellosis

Dysentery, Bacillary

Bacillary Dysentery

Shigella Boydii Infectious Disease

Shigella Flexneri Infectious Disease

Shigella Gastroenteritis

Shigella Sonnei Infectious Disease

Shigella Infections
Urinary Tract Infection

Urinary Tract Infections

Uti

Urinary Tract Infection Nos

Uti - [Urinary Tract Infection]

Uti Nos - [Urinary Tract Infection Nos]

Urosepsis Nos

E Coli Uti

E Coli Urinary Tract Infection

Escherichia Coli Uti
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13982 STX2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus STX2 VGNC VGNC:35438
Rattus norvegicus STX2 RGD RGD:2558
Canis familiaris STX2 VGNC VGNC:49890
Felis catus STX2 VGNC VGNC:65812
Mus musculus STX2 MGD MGI:108059
Macaca mulatta STX2 VGNC VGNC:78259
Others STX2 NCBI
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z