1. Gene
  2. Sparc - secreted acidic cysteine rich glycoprotein Gene

Sparc - secreted acidic cysteine rich glycoprotein Gene

种属: Mus musculus

同用名: ON; BM-40

基因 ID: 20692 | 基因类型: protein coding

关于 Sparc

功能概要

Enables calcium ion binding activity and extracellular matrix binding activity. Acts upstream of or within several processes, including bone development; cellular response to growth factor stimulus; and pigmentation. Located in extracellular matrix and extracellular space. Is expressed in several structures, including alimentary system; extraembryonic component; genitourinary system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in cervix carcinoma; endometrial carcinoma; and osteogenesis imperfecta type 17. Orthologous to human SPARC (secreted protein acidic and cysteine rich). [provided by Alliance of Genome Resources, Apr 2022]

Sparc 基因产物(2)

mRNA Protein Name
NM_001290817.1 NP_001277746.1 SPARC isoform 2 precursor
NM_009242.5 NP_033268.1 SPARC precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcium ion binding IDA
IDA: 通过直接分析推断
3427055 MGI
enables extracellular matrix binding IDA
IDA: 通过直接分析推断
18757743 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
21182835 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within bone development IMP
IMP: 通过突变表型推断
22876197 MGI
acts upstream of or within cellular response to growth factor stimulus IDA
IDA: 通过直接分析推断
7848824 MGI
acts upstream of or within pigmentation IMP
IMP: 通过突变表型推断
25340873 MGI
acts upstream of or within regulation of cell population proliferation IGI
IGI: 通过遗传相互作用推断
17299058 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular matrix IDA
IDA: 通过直接分析推断
8906420 MGI
located in extracellular space IDA
IDA: 通过直接分析推断
3427055 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

SPARC

basement-membrane protein 40

osteonectin

secreted protein acidic and rich in cysteine

重组 Sparc 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71086 SPARC Protein, Mouse (HEK293, His) P07214 (A18-I302) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sparc NCBI NCBI:6678
Macaca fascicularis Sparc NCBI NCBI:101925878
Rattus norvegicus Sparc NCBI NCBI:24791