2. Gene
  3. Sparc - secreted protein acidic and cysteine rich Gene

Sparc - secreted protein acidic and cysteine rich Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 24791 | 基因类型: protein coding

关于 Sparc

功能概要

Enables calcium ion binding activity. Involved in several processes, including animal organ development; response to L-ascorbic acid; and response to lead ion. Located in several cellular components, including extracellular space; nucleus; and vesicle. Is active in glutamatergic synapse. Biomarker of diabetic angiopathy; membranoproliferative glomerulonephritis; membranous glomerulonephritis; myocardial infarction; and stomach carcinoma. Human ortholog(s) of this gene implicated in cervix carcinoma; endometrial carcinoma; and osteogenesis imperfecta type 17. Orthologous to human SPARC (secreted protein acidic and cysteine rich). [provided by Alliance of Genome Resources, Apr 2022]

Sparc 基因产物(1)

mRNA Protein Name
NM_012656.2 NP_036788.1 SPARC precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcium ion binding IDA
IDA: 通过直接分析推断
2322281 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in heart development IEP
IEP: 通过表达模式推断
8287436 RGD
involved in inner ear development IEP
IEP: 通过表达模式推断
11335086 RGD
involved in lung development IMP
IMP: 通过突变表型推断
7654384 RGD
involved in ossification IEP
IEP: 通过表达模式推断
12365801 RGD
involved in regulation of synapse organization EXP
EXP: 通过实验结果推断
21788491 RGD
involved in regulation of synapse organization IDA
IDA: 通过直接分析推断
21788491 RGD
involved in response to L-ascorbic acid IEP
IEP: 通过表达模式推断
9495521 RGD
involved in response to cAMP IEP
IEP: 通过表达模式推断
10703670 RGD
involved in response to cadmium ion IEP
IEP: 通过表达模式推断
9232954 RGD
involved in response to calcium ion IEP
IEP: 通过表达模式推断
11897705 RGD
involved in response to cytokine IEP
IEP: 通过表达模式推断
10703670 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
11371715 RGD
involved in response to glucocorticoid IEP
IEP: 通过表达模式推断
9232954 RGD
involved in response to gravity IEP
IEP: 通过表达模式推断
17384275 RGD
involved in response to lead ion IEP
IEP: 通过表达模式推断
1412468 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
10703670 RGD
involved in response to peptide hormone IEP
IEP: 通过表达模式推断
15779007 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
2322281 RGD
is active in glutamatergic synapse EXP
EXP: 通过实验结果推断
21788491 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
21788491 RGD
is active in synapse EXP
EXP: 通过实验结果推断
16507876 RGD
is active in synapse IDA
IDA: 通过直接分析推断
16507876 RGD
located in vesicle IDA
IDA: 通过直接分析推断
18758911 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

SPARC

BM-40

ON

Secreted acidic cystein-rich glycoprotein (osteonectin)

basement-membrane protein 40

osteonectin

secreted acidic cysteine rich glycoprotein

secreted protein acidic and rich in cysteine

secreted protein, acidic, cysteine-rich (osteonectin)

重组 Sparc 蛋白

目录号 产品名 蛋白编号 纯度
HY-P73420 SPARC Protein, Rat (HEK293, His) P16975 (A18-I301) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13631 SPARC Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sparc NCBI NCBI:6678
Macaca fascicularis Sparc NCBI NCBI:101925878
Mus musculus Sparc NCBI NCBI:20692
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