1. Gene
  2. Serpini1 - serine (or cysteine) peptidase inhibitor, clade I, member 1 Gene

Serpini1 - serine (or cysteine) peptidase inhibitor, clade I, member 1 Gene

种属: Mus musculus

同用名: Ns; PI12; PI-12; Spi17

基因 ID: 20713 | 基因类型: protein coding

关于 Serpini1

功能概要

Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity; positive regulation of neuron projection development; and regulation of cell adhesion. Predicted to act upstream of or within negative regulation of peptidase activity. Located in neuronal cell body and secretory granule lumen. Is expressed in several structures, including early conceptus; enteric nervous system; intestine; retina; and secondary oocyte. Used to study familial encephalopathy with neuroserpin inclusion bodies. Human ortholog(s) of this gene implicated in familial encephalopathy with neuroserpin inclusion bodies. Orthologous to human SERPINI1 (serpin family I member 1). [provided by Alliance of Genome Resources, Apr 2022]

Serpini1 基因产物(2)

mRNA Protein Name
NM_001357514.1 NP_001344443.1 neuroserpin isoform 2 precursor
NM_009250.3 NP_033276.1 neuroserpin isoform 1 precursor
基因本体论
  • 细胞组分
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in neuronal cell body IDA
IDA: 通过直接分析推断
17040209 MGI
located in secretory granule lumen IDA
IDA: 通过直接分析推断
17040209 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

neuroserpin

peptidase inhibitor 12

protease inhibitor 17

serine protease inhibitor 17

serpin I1

重组 Serpini1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74703 Neuroserpin Protein, Mouse (HEK293, His) O35684 (T17-L410) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Serpini1 NCBI NCBI:5274