2. Gene
  3. Scarb1 - scavenger receptor class B, member 1 Gene

Scarb1 - scavenger receptor class B, member 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: CD36; Cla1; SRBI; Srb1; Cla-1; Hdlq1; SR-B1; SR-BI; Cd36l1; Chohd1; Hlb398; mSR-BI; D5Ertd460e

基因 ID: 20778 | 基因类型: protein coding

关于 Scarb1

功能概要

Enables amyloid-beta binding activity; Apolipoprotein binding activity; and high-density lipoprotein particle binding activity. Involved in several processes, including lipid homeostasis; lipid transport; and regulation of lipid metabolic process. Acts upstream of or within several processes, including blood vessel endothelial cell migration; Cholesterol catabolic process; and endothelial cell proliferation. Located in caveola; cell surface; and cytoplasm. Is integral component of plasma membrane. Is expressed in several structures, including alimentary system; brain; extraembryonic component; hemolymphoid system gland; and reproductive system. Orthologous to human SCARB1 (scavenger receptor class B member 1). [provided by Alliance of Genome Resources, Apr 2022]

Scarb1 基因产物(3)

mRNA Protein Name
NM_001205082.1 NP_001192011.1 scavenger receptor class B member 1 isoform 2
NM_001205083.1 NP_001192012.1 scavenger receptor class B member 1 isoform 3
NM_016741.2 NP_058021.1 scavenger receptor class B member 1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables amyloid-beta binding IGI
IGI: 通过遗传相互作用推断
11240025 MGI
enables apolipoprotein binding IPI
IPI: 通过物理相互作用推断
9254056 MGI
enables high-density lipoprotein particle binding IDA
IDA: 通过直接分析推断
14729860 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within blood vessel endothelial cell migration IMP
IMP: 通过突变表型推断
16339487 MGI
acts upstream of or within cholesterol catabolic process IDA
IDA: 通过直接分析推断
11278646 MGI
acts upstream of or within cholesterol catabolic process IMP
IMP: 通过突变表型推断
10559220 MGI
involved in cholesterol efflux IDA
IDA: 通过直接分析推断
14718538 MGI
involved in cholesterol efflux IMP
IMP: 通过突变表型推断
21481393 MGI
involved in cholesterol homeostasis IMP
IMP: 通过突变表型推断
19136670 MGI
involved in cholesterol import IDA
IDA: 通过直接分析推断
14718538 MGI
involved in cholesterol import IMP
IMP: 通过突变表型推断
18175806 MGI
acts upstream of or within cholesterol transport IDA
IDA: 通过直接分析推断
8753864 MGI
acts upstream of or within cholesterol transport IMP
IMP: 通过突变表型推断
10559220 MGI
acts upstream of or within endothelial cell proliferation IMP
IMP: 通过突变表型推断
16339487 MGI
involved in high-density lipoprotein particle remodeling IMP
IMP: 通过突变表型推断
15210842 MGI
acts upstream of or within intestinal lipid absorption IMP
IMP: 通过突变表型推断
25701869 MGI
involved in low-density lipoprotein particle clearance IMP
IMP: 通过突变表型推断
18175806 MGI
involved in phospholipid transport IMP
IMP: 通过突变表型推断
18175806 MGI
involved in positive regulation of triglyceride biosynthetic process IMP
IMP: 通过突变表型推断
18175806 MGI
involved in regulation of phosphatidylcholine catabolic process IMP
IMP: 通过突变表型推断
18175806 MGI
involved in reverse cholesterol transport IMP
IMP: 通过突变表型推断
19136670 MGI
involved in triglyceride homeostasis IMP
IMP: 通过突变表型推断
19136670 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in caveola IDA
IDA: 通过直接分析推断
9148942 MGI
located in cell surface IDA
IDA: 通过直接分析推断
21481393 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
21481393 MGI
located in membrane IDA
IDA: 通过直接分析推断
9148942 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
9148942 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

scavenger receptor class B member 1

HDL QTL 1

scavenger receptor class B type I

scavenger receptor class B1

重组 Scarb1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76086 SR-BI/SCARB1 Protein, Mouse (HEK293, His-Fc) Q61009 (P33-V440) ≥95%
HY-P76087 SR-BI/SCARB1 Protein, Mouse (HEK293, His) Q61009/NP_058021.1 (P33-V440) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12488 SCARB1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Scarb1 NCBI NCBI:949
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