2. Gene
  3. Syn1 - synapsin I Gene

Syn1 - synapsin I Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Syn-1; Syn1-S

基因 ID: 20964 | 基因类型: protein coding

关于 Syn1

功能概要

Enables identical protein binding activity and protein kinase binding activity. Involved in regulation of synaptic vesicle cycle and synaptic vesicle clustering. Acts upstream of or within neurotransmitter secretion. Located in several cellular components, including Schaffer collateral - CA1 synapse; synaptic vesicle membrane; and synaptonemal complex. Is expressed in diaphragm; intercostal muscle; molar; nervous system; and sensory organ. Used to study autism spectrum disorder. Human ortholog(s) of this gene implicated in X-linked epilepsy with variable learning disabilities and behavior disorders and non-syndromic X-linked intellectual disability 50. Orthologous to human SYN1 (synapsin I). [provided by Alliance of Genome Resources, Apr 2022]

Syn1 基因产物(2)

mRNA Protein Name
NM_001110780.1 NP_001104250.1 synapsin-1 isoform b
NM_013680.4 NP_038708.3 synapsin-1 isoform a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
15071120 MGI
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
21307259 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within neurotransmitter secretion IGI
IGI: 通过遗传相互作用推断
7777057 MGI
acts upstream of or within neurotransmitter secretion IMP
IMP: 通过突变表型推断
7777057 MGI
involved in regulation of synaptic vesicle cycle IDA
IDA: 通过直接分析推断
8794863 MGI
involved in regulation of synaptic vesicle cycle IMP
IMP: 通过突变表型推断
8794863 MGI
involved in synaptic vesicle cycle IDA
IDA: 通过直接分析推断
7902212 MGI
involved in synaptic vesicle cycle IMP
IMP: 通过突变表型推断
7902212 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in Schaffer collateral - CA1 synapse IDA
IDA: 通过直接分析推断
7902212 MGI
is active in Schaffer collateral - CA1 synapse IMP
IMP: 通过突变表型推断
7902212 MGI
is active in axon IDA
IDA: 通过直接分析推断
17634368 MGI
located in axon IDA
IDA: 通过直接分析推断
15255972 MGI
is active in cell body IDA
IDA: 通过直接分析推断
17634368 MGI
is active in dendrite IDA
IDA: 通过直接分析推断
17634368 MGI
located in postsynaptic density IDA
IDA: 通过直接分析推断
17114649 MGI
located in presynapse IDA
IDA: 通过直接分析推断
27759003 MGI
located in presynaptic active zone IDA
IDA: 通过直接分析推断
16621800 MGI
located in synapse IDA
IDA: 通过直接分析推断
14622577 MGI
located in synaptic vesicle membrane IDA
IDA: 通过直接分析推断
15071120 MGI
located in synaptonemal complex IDA
IDA: 通过直接分析推断
14736746 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

synapsin-1

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14079 SYN1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Syn1 NCBI NCBI:6853
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