Efemp1 - epidermal growth factor-containing fibulin-like extracellular matrix protein 1 Gene

种属: Mus musculus

关于 Efemp1

功能概要

Predicted to enable epidermal growth factor receptor binding activity and epidermal growth factor-activated receptor activity. Predicted to be involved in several processes, including negative regulation of chondrocyte differentiation; peptidyl-tyrosine phosphorylation; and regulation of cell projection organization. Located in collagen-containing extracellular matrix and extracellular space. Is expressed in several structures, including alimentary system; brain; embryo mesenchyme; male reproductive gland or organ; and skeleton. Used to study Doyne honeycomb retinal dystrophy. Human ortholog(s) of this gene implicated in Doyne honeycomb retinal dystrophy. Orthologous to human EFEMP1 (EGF containing fibulin extracellular Matrix Protein 1). [provided by Alliance of Genome Resources, Apr 2022]