1. Gene
  2. Tnfsf10 - tumor necrosis factor (ligand) superfamily, member 10 Gene

Tnfsf10 - tumor necrosis factor (ligand) superfamily, member 10 Gene

种属: Mus musculus

同用名: TL2; Ly81; Trail; APO-2L; Tnlg6a; A330042I21Rik

基因 ID: 22035 | 基因类型: protein coding

关于 Tnfsf10

功能概要

Enables TRAIL binding activity and tumor necrosis factor receptor superfamily binding activity. Acts upstream of or within positive regulation of extrinsic apoptotic signaling pathway. Predicted to be located in extracellular space and plasma membrane. Predicted to be integral component of membrane. Is expressed in central nervous system; genitourinary system; gut; and retina. Human ortholog(s) of this gene implicated in arteriosclerosis and small cell carcinoma. Orthologous to human TNFSF10 (TNF Superfamily member 10). [provided by Alliance of Genome Resources, Apr 2022]

Tnfsf10 基因产物(1)

mRNA Protein Name
NM_009425.2 NP_033451.1 tumor necrosis factor ligand superfamily member 10
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables TRAIL binding IDA
IDA: 通过直接分析推断
12466268 MGI
enables tumor necrosis factor receptor superfamily binding IPI
IPI: 通过物理相互作用推断
12466268 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within positive regulation of extrinsic apoptotic signaling pathway IDA
IDA: 通过直接分析推断
15632112 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

tumor necrosis factor ligand superfamily member 10

TNF-related apoptosis-inducing ligand

TRAIL/APO2L

tumor necrosis factor ligand 6a

重组 Tnfsf10 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7089AF Animal-Free TRAIL/TNFSF10 Protein, Mouse (His) P50592 (P118-N291) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tnfsf10 NCBI NCBI:8743
Macaca mulatta Tnfsf10 NCBI NCBI:694451