Tuba1a - tubulin, alpha 1A Gene

种属: Mus musculus

同用名: Tuba1; Tuba-1

关于 Tuba1a

功能概要

Predicted to enable GTP binding activity; identical protein binding activity; and protein domain specific binding activity. Predicted to be a structural constituent of Cytoskeleton. Involved in regulation of synapse organization. Located in cytoplasmic microtubule. Is active in neuromuscular junction. Is expressed in several structures, including brain; hemolymphoid system gland; lateral plate mesoderm; liver; and testis. Used to study congenital nervous system abnormality and lissencephaly. Human ortholog(s) of this gene implicated in lissencephaly; lissencephaly 3; microcephaly; and visual epilepsy. Orthologous to human TUBA1A (tubulin alpha 1a). [provided by Alliance of Genome Resources, Apr 2022]