2. Gene
  3. Vldlr - very low density lipoprotein receptor Gene

Vldlr - very low density lipoprotein receptor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 22359 | 基因类型: protein coding

关于 Vldlr

功能概要

Enables reelin receptor activity. Involved in dendrite morphogenesis; positive regulation of dendrite development; and reelin-mediated signaling pathway. Acts upstream of or within positive regulation of protein kinase activity and ventral spinal cord development. Located in extracellular space. Is expressed in several structures, including alimentary system; genitourinary system; musculoskeletal system; nervous system; and sensory organ. Used to study age related macular degeneration 1. Human ortholog(s) of this gene implicated in Alzheimer's disease; cerebellar ataxia, mental retardation and dysequlibrium syndrome; and dementia. Orthologous to human VLDLR (very low density lipoprotein receptor). [provided by Alliance of Genome Resources, Apr 2022]

Vldlr 基因产物(4)

mRNA Protein Name
NM_001161420.1 NP_001154892.1 very low-density lipoprotein receptor isoform b precursor
NM_001347441.1 NP_001334370.1 very low-density lipoprotein receptor isoform c precursor
NM_001412816.1 NP_001399745.1 very low-density lipoprotein receptor isoform c precursor
NM_013703.2 NP_038731.2 very low-density lipoprotein receptor isoform a precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15249135 MGI
enables reelin receptor activity IDA
IDA: 通过直接分析推断
10571241 MGI
enables reelin receptor activity IGI
IGI: 通过遗传相互作用推断
18778775 MGI
enables reelin receptor activity IMP
IMP: 通过突变表型推断
18778775 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in dendrite morphogenesis IMP
IMP: 通过突变表型推断
18778775 MGI
involved in positive regulation of dendrite development IGI
IGI: 通过遗传相互作用推断
18778775 MGI
acts upstream of or within positive regulation of protein kinase activity IGI
IGI: 通过遗传相互作用推断
12526740 MGI
involved in reelin-mediated signaling pathway IDA
IDA: 通过直接分析推断
10571241 MGI
involved in reelin-mediated signaling pathway IGI
IGI: 通过遗传相互作用推断
18778775 MGI
involved in regulation of synapse assembly IDA
IDA: 通过直接分析推断
25644714 MGI
involved in regulation of synapse assembly IMP
IMP: 通过突变表型推断
25644714 MGI
involved in ventral spinal cord development IEP
IEP: 通过表达模式推断
20711475 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
15950758 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
25644714 MGI
is active in synapse IDA
IDA: 通过直接分析推断
25644714 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

very low-density lipoprotein receptor

VLDL receptor

VLDL-R

重组 Vldlr 蛋白

目录号 产品名 蛋白编号 纯度
HY-P78049 VLDLR Protein, Mouse (HEK293, His) P98156 (G28-S797) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15661 VLDLR Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Vldlr NCBI NCBI:7436
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