1. Gene
  2. Myrf - myelin regulatory factor Gene

Myrf - myelin regulatory factor Gene

种属: Mus musculus

同用名: Mrf; Gm98; Gm1804; 6030439E18

基因 ID: 225908 | 基因类型: protein coding

关于 Myrf

功能概要

Enables DNA binding activity and DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in several processes, including central nervous system myelin maintenance; positive regulation of myelination; and regulation of transcription, DNA-templated. Located in endoplasmic reticulum membrane and nucleus. Is expressed in pigmented retinal epithelium; spinal cord; and spinal cord marginal layer. Orthologous to human MYRF (myelin regulatory factor). [provided by Alliance of Genome Resources, Apr 2022]

Myrf 基因产物(2)

mRNA Protein Name
NM_001033481.2 NP_001028653.1 myelin regulatory factor isoform 1
NM_001404113.1 NP_001391042.1 myelin regulatory factor isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
24204311 MGI
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
24204311 MGI
enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
31828317 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
30249802 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in central nervous system myelin maintenance IMP
IMP: 通过突变表型推断
22956843 MGI
involved in central nervous system myelination IMP
IMP: 通过突变表型推断
19596243 MGI
involved in oligodendrocyte development IDA
IDA: 通过直接分析推断
31828317 MGI
involved in oligodendrocyte development IMP
IMP: 通过突变表型推断
19596243 MGI
involved in oligodendrocyte differentiation IMP
IMP: 通过突变表型推断
22956843 MGI
involved in positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
19596243 MGI
involved in positive regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
22956843 MGI
involved in positive regulation of myelination IMP
IMP: 通过突变表型推断
19596243 MGI
involved in protein autoprocessing IDA
IDA: 通过直接分析推断
30249802 MGI
involved in regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
31828317 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
30249802 MGI
located in endoplasmic reticulum membrane IDA
IDA: 通过直接分析推断
30249802 MGI
located in nucleus IDA
IDA: 通过直接分析推断
19596243 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

myelin regulatory factor

myelin gene regulatory factor

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Myrf NCBI NCBI:745