1. Gene
  2. MAST3 - microtubule associated serine/threonine kinase 3 Gene

MAST3 - microtubule associated serine/threonine kinase 3 Gene

中文名称:微管相关丝氨酸/苏氨酸激酶 3

种属: Homo sapiens

同用名: DEE108

基因 ID: 23031 | 基因类型: protein coding

关于 MAST3

Cytogenetic location: 19p13.11 Genomic coordinates (GRCh38): 19:18,097,778-18,151,687 (from NCBI)

This gene has 10 transcripts (splice variants), 273 orthologues and 13 paralogues. Broad expression in brain (RPKM 16.8), spleen (RPKM 6.6) and 24 other tissues.

功能概要

预测启用蛋白质丝氨酸/苏氨酸激酶活性。预计参与细胞骨架组织;细胞内信号转导;和肽基丝氨酸磷酸化。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in Cytoskeleton organization; intracellular signal transduction; and peptidyl-serine phosphorylation. [provided by Alliance of Genome Resources, Apr 2022]

MAST3 基因产物(22)

mRNA Protein Name
NM_001393501.1 NP_001380430.1 microtubule-associated serine/threonine-protein kinase 3 isoform 1
NM_001393502.1 NP_001380431.1 microtubule-associated serine/threonine-protein kinase 3 isoform 2
NM_001393503.1 NP_001380432.1 microtubule-associated serine/threonine-protein kinase 3 isoform 3
NM_001393504.1 NP_001380433.1 microtubule-associated serine/threonine-protein kinase 3 isoform 4
NM_001393505.1 NP_001380434.1 microtubule-associated serine/threonine-protein kinase 3 isoform 5
NM_001393506.1 NP_001380435.1 microtubule-associated serine/threonine-protein kinase 3 isoform 6
NM_001393507.1 NP_001380436.1 microtubule-associated serine/threonine-protein kinase 3 isoform 7
NM_001393508.1 NP_001380437.1 microtubule-associated serine/threonine-protein kinase 3 isoform 8
NM_001393509.1 NP_001380438.1 microtubule-associated serine/threonine-protein kinase 3 isoform 9
NM_001393510.1 NP_001380439.1 microtubule-associated serine/threonine-protein kinase 3 isoform 10
NM_001393511.1 NP_001380440.1 microtubule-associated serine/threonine-protein kinase 3 isoform 11
NM_001393512.1 NP_001380441.1 microtubule-associated serine/threonine-protein kinase 3 isoform 12
NM_001393513.1 NP_001380442.1 microtubule-associated serine/threonine-protein kinase 3 isoform 13
NM_001393514.1 NP_001380443.1 microtubule-associated serine/threonine-protein kinase 3 isoform 14
NM_001393515.1 NP_001380444.1 microtubule-associated serine/threonine-protein kinase 3 isoform 15
NM_001393516.1 NP_001380445.1 microtubule-associated serine/threonine-protein kinase 3 isoform 16
NM_001393517.1 NP_001380446.1 microtubule-associated serine/threonine-protein kinase 3 isoform 17
NM_001393518.1 NP_001380447.1 microtubule-associated serine/threonine-protein kinase 3 isoform 18
NM_001393519.1 NP_001380448.1 microtubule-associated serine/threonine-protein kinase 3 isoform 19
NM_001393520.1 NP_001380449.1 microtubule-associated serine/threonine-protein kinase 3 isoform 21
NM_001393521.1 NP_001380450.1 microtubule-associated serine/threonine-protein kinase 3 isoform 22
NM_015016.2 NP_055831.1 microtubule-associated serine/threonine-protein kinase 3 isoform 20

MAST3 蛋白结构

DUF1908

DUF1908: Domain of unknown function (DUF1908) (58 - 332)

Pkinase

Pkinase: Protein kinase domain (367 - 640)

PDZ

PDZ: PDZ domain (Also known as DHR or GLGF) (976 - 1032)

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  • 1309 a.a.
蛋白主名 其他名称

microtubule-associated serine/threonine-protein kinase 3

MAST3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
MAST3 O60307 PTEN Homo sapiens P60484
Beta Galactosidase
15951562
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Inflammatory Bowel Disease 6

IBD6

Mega-Corpus-Callosum Syndrome With Cerebellar Hypoplasia And Cortical Malformations

MCCCHCM

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Canis familiaris MAST3 VGNC VGNC:43034
Mus musculus MAST3 MGD MGI:2683541
Rattus norvegicus MAST3 RGD RGD:1587639
Bos taurus MAST3 VGNC VGNC:31259
Felis catus MAST3 VGNC VGNC:63394
Macaca mulatta MAST3 VGNC VGNC:74533