Nppa - natriuretic peptide type A Gene

种属: Mus musculus

同用名: ANP; Anf; CDD; Pnd

关于 Nppa

功能概要

This gene encodes members of the natriuretic family of Peptides that play an important role in the control of extracellular fluid volume and electrolyte homeostasis. The encoded protein precursor undergoes proteolytic processing to generate multiple functional Peptides. Mice lacking the encoded Peptides exhibit salt-sensitive hypertension. The transgenic overexpression of the encoded Peptides in mice decreases arterial blood pressure without inducing diuresis and natriuresis. This gene is located adjacent to another member of the natriuretic family of Peptides on chromosome 4. [provided by RefSeq, Oct 2015]