2. Gene
  3. KIF13B - kinesin family member 13B Gene

KIF13B - kinesin family member 13B Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：驱动蛋白家族成员 13B

种属: Homo sapiens

同用名: GAKIN

基因 ID: 23303 | 基因类型: protein coding

关于 KIF13B

Cytogenetic location: 8p12 Genomic coordinates (GRCh38): 8:29,067,278-29,263,388 (from NCBI)

This gene has 6 transcripts (splice variants), 277 orthologues and 41 paralogues. Ubiquitous expression in kidney (RPKM 15.2), colon (RPKM 14.6) and 25 other tissues.

功能概要

启用 14-3-3 蛋白结合活性和蛋白激酶结合活性。参与轴突发生的调节。位于轴突和细胞质中。 [由基因组资源联盟提供，2022 年 4 月]

Enables 14-3-3 protein binding activity and protein kinase binding activity. Involved in regulation of axonogenesis. Located in axon and cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

KIF13B 基因产物(1)

mRNA Protein Name
NM_015254.4 NP_056069.2 kinesin-like protein KIF13B
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 14-3-3 protein binding IDA
IDA: 通过直接分析推断
20194617 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
10859302 GOA
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
10859302 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in regulation of axonogenesis IDA
IDA: 通过直接分析推断
20194617 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
20194617 GOA
located in cytoplasm IDA
IDA: 通过直接分析推断
10859302 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

KIF13B 蛋白结构

Kinesin

Kinesin: Kinesin motor domain (11 - 353)

FHA

FHA: FHA domain (472 - 535)

KIF1B

KIF1B: Kinesin protein 1B (756 - 802)

DUF3694

DUF3694: Kinesin protein (1003 - 1061)

DUF3694

DUF3694: Kinesin protein (1207 - 1280)

CAP_GLY

CAP_GLY: CAP-Gly domain (1705 - 1767)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1500
  • 1826 a.a.
蛋白主名 其他名称

kinesin-like protein KIF13B

guanylate kinase associated kinesin

KIF13B 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
KIF13B Q9NQT8 DLG1 Homo sapiens Q12959-2
Pull Down
10859302
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Deafness, Autosomal Recessive 84a

DFNB84A

Deafness, Autosomal Recessive 84

Autosomal Recessive Nonsyndromic Deafness 84a

Dfnb84

Deafness, Autosomal Recessive 84a, With Vestibular Dysfunction

Autosomal Recessive Deafness 84a

Autosomal Recessive Deafness 84a With Vestibular Dysfunction

Deafness, Autosomal Recessive, 84a

Deafness Autosomal Recessive 84

Deafness Autosomal Recessive 84a With Vestibular Dysfunction

Non-Syndromic Neurosensory Deafness Autosomal Recessive Type 84

Deafness, Autosomal Recessive, Type 84a
Meester-Loeys Syndrome

MRLS
Congenital Fibrosis Of The Extraocular Muscles

Congenital Fibrosis Of Extraocular Muscles

Cfeom

Feom

Congenital External Ophthalmoplegia

Congenital Fibrosis Syndrome

General Fibrosis Syndrome
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07260 KIF13B Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris KIF13B VGNC VGNC:42382
Bos taurus KIF13B VGNC VGNC:30582
Mus musculus KIF13B MGD MGI:1098265
Macaca mulatta KIF13B VGNC VGNC:99471
Rattus norvegicus KIF13B RGD RGD:1303307
Felis catus KIF13B VGNC VGNC:82484
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