2. Gene
  3. USP24 - ubiquitin specific peptidase 24 Gene

USP24 - ubiquitin specific peptidase 24 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：泛素特异性肽酶 24

种属: Homo sapiens

基因 ID: 23358 | 基因类型: protein coding

关于 USP24

Cytogenetic location: 1p32.3 Genomic coordinates (GRCh38): 1:55,066,359-55,215,364 (from NCBI)

This gene has 7 transcripts (splice variants), 164 orthologues and 71 paralogues. Ubiquitous expression in bone marrow (RPKM 9.9), lymph node (RPKM 9.7) and 25 other tissues.

功能概要

泛素对细胞蛋白质的修饰是一种重要的调节机制，由多种泛素结合酶和去泛素化酶的协调作用控制。 USP24 属于一大类半胱氨酸蛋白酶，可作为去泛素化酶发挥作用 (Quesada 等人，2004 年 [PubMed 14715245]) 。[OMIM 提供，2008 年 3 月]

Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating Enzymes. USP24 belongs to a large family of cysteine proteases that function as deubiquitinating Enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Mar 2008]

USP24 基因产物(1)

mRNA Protein Name
NM_015306.3 NP_056121.2 ubiquitin carboxyl-terminal hydrolase 24
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32814053 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

USP24 蛋白结构

UCH

UCH: Ubiquitin carboxyl-terminal hydrolase (1689 - 2039)

  • 0
  • 500
  • 1000
  • 1500
  • 2000
  • 2620 a.a.
蛋白主名 其他名称

ubiquitin carboxyl-terminal hydrolase 24

deubiquitinating enzyme 24

关联疾病

疾病名称 别名
Non-Syndromic X-Linked Intellectual Disability 99

Mrx99

X-Linked Mental Retardation 99
Parkinson Disease, Late-Onset

Parkinson Disease

Parkinson'S Disease

PD

PARK

Parkinson Disease, Susceptibility To

Late Onset Parkinson'S Disease

Late Onset Parkinson Disease

Paralysis Agitans

Primary Parkinsonism

Idiopathic Parkinson Disease

Parkinson'S

Parkinson Disease, Late-Onset, Susceptibility To

Parkinson Disease, Age Of Onset, Modifier

Lewy Body Parkinson Disease

Idiopathic Parkinson'S Disease

Pd - [Parkinson Disease]

Parkinson Disease Nos

Parkinson, Nos

Primary Parkinson Disease
Fanconi Anemia, Complementation Group A

Fanconi Anemia

Fanconi Pancytopenia

Fanconi Anemia Complementation Group A

FANCA

Fa

Fanconi Panmyelopathy

Fanconi'S Anemia

Fanconi Anaemia

Fanconi'S Anaemia

Fanconi Hypoplastic Anemia

Estren-Dameshek Variant Of Fanconi Anemia

Estren-Dameshek Variant Of Fanconi Pancytopenia

Fanconi Anemia Estren-Dameshek Variant

Fanconis Anemia
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-111408 EOAI3402143 Inhibitor 98.95% 否
HY-RS15534 USP24 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta USP24 VGNC VGNC:78743
Rattus norvegicus USP24 RGD RGD:1306799
Felis catus USP24 VGNC VGNC:66874
Mus musculus USP24 MGD MGI:1919936
Bos taurus USP24 VGNC VGNC:36717
Canis familiaris USP24 VGNC VGNC:48183
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z