FNTA - farnesyltransferase, CAAX box, alpha Gene

中文名称：法尼基转移酶，CAAX 盒，alpha

种属: Homo sapiens

同用名: FPTA; PTAR2; PGGT1A

关于 FNTA

功能概要

异戊二烯基转移酶可以将硫醚键中的法尼基或香叶基香叶基连接到具有 C 末端 CAAX 盒的蛋白质的半胱氨酸残基上。 CAAX 香叶基香叶基转移酶和 CAAX 法尼基转移酶是异二聚体，它们共享相同的 α 亚基但具有不同的 β 亚基。该基因编码这些转移酶的α亚基。可变剪接导致多个转录本变体。已在 11 号和 13 号染色体上鉴定出相关的假基因。[RefSeq 提供，2010 年 5 月]

Prenyltransferases can attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of proteins with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 11 and 13. [provided by RefSeq, May 2010]