2. Gene
  3. CDK20 - cyclin dependent kinase 20 Gene

CDK20 - cyclin dependent kinase 20 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：细胞周期蛋白依赖性激酶 20

种属: Homo sapiens

同用名: P42; CCRK; CDCH; PNQALRE

基因 ID: 23552 | 基因类型: protein coding

关于 CDK20

Cytogenetic location: 9q22.1 Genomic coordinates (GRCh38): 9:87,966,441-87,974,533 (from NCBI)

This gene has 10 transcripts (splice variants), 199 orthologues and 26 paralogues. Broad expression in testis (RPKM 10.2), adrenal (RPKM 7.6) and 24 other tissues.

功能概要

由该基因编码的蛋白质包含与细胞周期蛋白依赖性蛋白激酶最密切相关的激酶结构域。编码的激酶可激活细胞周期蛋白依赖性激酶 2，并参与细胞生长。已经报道了编码不同亚型的可变剪接转录物变体。[RefSeq 提供，2009 年 12 月]

The protein encoded by this gene contains a kinase domain most closely related to the cyclin-dependent protein kinases. The encoded kinase may activate cyclin-dependent kinase 2 and is involved in cell growth. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Dec 2009]

CDK20 基因产物(5)

mRNA Protein Name
NM_001039803.3 NP_001034892.1 cyclin-dependent kinase 20 isoform 3
NM_001170639.2 NP_001164110.1 cyclin-dependent kinase 20 isoform 4
NM_001170640.2 NP_001164111.1 cyclin-dependent kinase 20 isoform 5
NM_012119.5 NP_036251.2 cyclin-dependent kinase 20 isoform 2
NM_178432.4 NP_848519.1 cyclin-dependent kinase 20 isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
21986944 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

CDK20 蛋白结构

Pkinase

Pkinase: Protein kinase domain (4 - 288)

  • 0
  • 100
  • 200
  • 300
  • 346 a.a.
蛋白主名 其他名称

cyclin-dependent kinase 20

CAK-kinase p42

CDK20 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
CDK20 Q8IZL9 TRIM2 Homo sapiens Q9C040
Y2H Prey Pooling
26871637
种属内
CDK20 Q8IZL9 TRIM2 Homo sapiens Q9C040
Validated Y2H
26871637
种属内
CDK20 Q8IZL9 TRIM2 Homo sapiens Q9C040
Y2H Array
26871637
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Attention Deficit-Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder

ADHD

Attention Deficit Disorder

Attention Deficit-Hyperactivity Disorder, Susceptibility To

Attention Deficit Disorder With Hyperactivity

Hyperkinetic Disorder

Hyperactivity Of Childhood

Attention-Deficit/Hyperactivity Disorder

Add

Addh

Attention Deficit

Attention Deficit Disorder Of Childhood With Hyperactivity

Attention Deficit Disorder With Hyperactivity Syndrome

Hyperkinetic Syndrome

Attention-Deficit Hyperactivity Disorder

Attention-Deficit/Hyperactivity Disorder, Predominantly Inattentive Type

Disturbance Of Activity And Attention

Disorder Of Activity And Attention

Adhd - [Attention Deficit Hyperactivity Disorder]

Hyperkinetic Disorders

Disorder Of Activity And Attention With Hyperkinesia

Attention Deficit Syndrome With Hyperactivity
Endocrine-Cerebroosteodysplasia

Endocrine-Cerebro-Osteodysplasia Syndrome

ECO

Eco Syndrome
Nephrotic Syndrome, Type 22

NPHS22

Nephrotic Syndrome Type 22

Nephrotic Syndrome 22
Bardet-Biedl Syndrome

Bbs

Biedl-Bardet Syndrome
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02377 CDK20 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus CDK20 VGNC VGNC:27124
Macaca mulatta CDK20 VGNC VGNC:71070
Felis catus CDK20 VGNC VGNC:60698
Rattus norvegicus CDK20 RGD RGD:1305219
Canis familiaris CDK20 VGNC VGNC:39052
Mus musculus CDK20 MGD MGI:2145349
Others CDK20 NCBI
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