CDC42EP4 - CDC42 effector protein 4 Gene

中文名称：CDC42 效应蛋白 4

种属: Homo sapiens

同用名: CEP4; BORG4; KAIA1777

关于 CDC42EP4

功能概要

该基因的产物是 CDC42 结合蛋白家族的成员。该家族的成员与 Rho 家族 GTP 酶相互作用并调节肌动蛋白细胞骨架的组织。这种蛋白质已被证明以 GTP 依赖性方式结合 CDC42 和 TC10 GTP 酶。当在成纤维细胞中过表达时，该蛋白能够诱导伪足形成，这表明它在诱导肌动蛋白丝组装和细胞形状控制中发挥作用。[RefSeq 提供，2008 年 7 月]

The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin Cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control. [provided by RefSeq, Jul 2008]