2. Gene
  3. Grem2 - gremlin 2, DAN family BMP antagonist Gene

Grem2 - gremlin 2, DAN family BMP antagonist Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Prdc; Gremlin2

基因 ID: 23893 | 基因类型: protein coding

关于 Grem2

功能概要

Enables BMP binding activity; heparin binding activity; and identical protein binding activity. Involved in several processes, including determination of dorsal identity; embryonic body morphogenesis; and regulation of signal transduction. Located in extracellular space. Is expressed in several structures, including chondrocranium; integument; intestine smooth muscle circular layer; lung; and neural tube. Human ortholog(s) of this gene implicated in tooth agenesis. Orthologous to human GREM2 (gremlin 2, DAN family BMP antagonist). [provided by Alliance of Genome Resources, Apr 2022]

Grem2 基因产物(1)

mRNA Protein Name
NM_011825.1 NP_035955.1 gremlin-2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables BMP binding IMP
IMP: 通过突变表型推断
23063586 MGI
enables heparin binding IDA
IDA: 通过直接分析推断
23850456 MGI
enables identical protein binding IMP
IMP: 通过突变表型推断
23063586 MGI
enables identical protein binding IPI
IPI: 通过物理相互作用推断
23850456 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cytokine-mediated signaling pathway IMP
IMP: 通过突变表型推断
23850456 MGI
involved in determination of dorsal identity IMP
IMP: 通过突变表型推断
23063586 MGI
involved in embryonic body morphogenesis IMP
IMP: 通过突变表型推断
23850456 MGI
involved in negative regulation of BMP signaling pathway IMP
IMP: 通过突变表型推断
23063586 MGI
involved in regulation of cytokine activity IMP
IMP: 通过突变表型推断
23850456 MGI
involved in sequestering of BMP from receptor via BMP binding IMP
IMP: 通过突变表型推断
23063586 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IMP
IMP: 通过突变表型推断
23063586 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

gremlin-2

Gremlin1

cysteine knot superfamily 1, BMP antagonist 2

gremlin 2 homolog, cysteine knot superfamily

protein related to DAN and cerberus

重组 Grem2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P79104 PRDC/GREM2 Protein, Mouse O88273/NP_035955 (R22-Q168) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05785 GREM2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Grem2 NCBI NCBI:64388
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z