1. Gene
  2. Ccl19 - chemokine (C-C motif) ligand 19 Gene

Ccl19 - chemokine (C-C motif) ligand 19 Gene

种属: Mus musculus

同用名: ELC; CKb11; MIP3B; Gm2023; Scya19; exodus-3

基因 ID: 24047 | 基因类型: protein coding

关于 Ccl19

功能概要

Enables CCR7 Chemokine Receptor binding activity and chemokine activity. Involved in several processes, including positive regulation of T cell activation; positive regulation of cellular component organization; and positive regulation of cytokine production. Located in external side of plasma membrane. Is expressed in Peyer's patch; inguinal lymph node; thymus; and thymus primordium. Orthologous to human CCL19 (C-C motif chemokine ligand 19). [provided by Alliance of Genome Resources, Apr 2022]

Ccl19 基因产物(1)

mRNA Protein Name
NM_011888.4 NP_036018.1 C-C motif chemokine 19 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables CCR7 chemokine receptor binding IPI
IPI: 通过物理相互作用推断
9507024 MGI
enables chemokine activity IDA
IDA: 通过直接分析推断
12200351 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in T cell costimulation IDA
IDA: 通过直接分析推断
15845453 MGI
involved in cell maturation IDA
IDA: 通过直接分析推断
15845453 MGI
involved in dendritic cell chemotaxis IDA
IDA: 通过直接分析推断
12200351 MGI
involved in immunological synapse formation IDA
IDA: 通过直接分析推断
15845453 MGI
involved in mature conventional dendritic cell differentiation IDA
IDA: 通过直接分析推断
15845453 MGI
involved in positive regulation of GTPase activity IDA
IDA: 通过直接分析推断
12609829 MGI
acts upstream of positive regulation of JUN kinase activity IDA
IDA: 通过直接分析推断
16027136 MGI
involved in positive regulation of T cell proliferation IDA
IDA: 通过直接分析推断
15845453 MGI
involved in positive regulation of T-helper 1 cell differentiation IDA
IDA: 通过直接分析推断
15845453 MGI
involved in positive regulation of chemotaxis IDA
IDA: 通过直接分析推断
9507024 MGI
involved in positive regulation of dendritic cell antigen processing and presentation IMP
IMP: 通过突变表型推断
15845453 MGI
involved in positive regulation of dendritic cell dendrite assembly IDA
IDA: 通过直接分析推断
12200351 MGI
involved in positive regulation of endocytosis IDA
IDA: 通过直接分析推断
16027136 MGI
involved in positive regulation of glycoprotein biosynthetic process IDA
IDA: 通过直接分析推断
15845453 MGI
involved in positive regulation of interleukin-1 beta production IDA
IDA: 通过直接分析推断
15845453 MGI
acts upstream of positive regulation of interleukin-12 production IDA
IDA: 通过直接分析推断
15845453 MGI
involved in positive regulation of receptor-mediated endocytosis IDA
IDA: 通过直接分析推断
12609829 MGI
involved in positive regulation of tumor necrosis factor production IDA
IDA: 通过直接分析推断
15845453 MGI
involved in regulation of cell projection assembly IDA
IDA: 通过直接分析推断
12200351 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
19008373 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

C-C motif chemokine 19

EBI-1 ligand chemokine

EBI1 ligand chemokine

EBV-induced molecule 1 ligand chemokine

chemokine CCL19

epstein-Barr virus-induced molecule 1 ligand chemokine

small-inducible cytokine A19

重组 Ccl19 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7264 MIP-3 beta/CCL19 Protein, Mouse O70460 (G26-S108) ≥95%
HY-P7264A MIP-3 beta/CCL19 Protein, Mouse (sf9, His) O70460 (G26-S108) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ccl19 NCBI NCBI:6363