2. Gene
  3. Lrrtm4 - leucine rich repeat transmembrane neuronal 4 Gene

Lrrtm4 - leucine rich repeat transmembrane neuronal 4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: A230052N11; 7530419J18Rik

基因 ID: 243499 | 基因类型: protein coding

关于 Lrrtm4

功能概要

Enables heparan sulfate proteoglycan binding activity. Involved in regulation of synapse assembly. Acts upstream of or within AMPA glutamate receptor clustering; positive regulation of synapse assembly; and regulation of presynaptic membrane organization. Located in glutamatergic synapse and postsynaptic membrane. Part of AMPA glutamate receptor complex. Is expressed in several structures, including central nervous system; embryo mesenchyme; and future midbrain. Orthologous to human LRRTM4 (leucine rich repeat transmembrane neuronal 4). [provided by Alliance of Genome Resources, Apr 2022]

Lrrtm4 基因产物(4)

mRNA Protein Name
NM_001134743.1 NP_001128215.1 leucine-rich repeat transmembrane neuronal protein 4 isoform 3 precursor
NM_001282102.1 NP_001269031.1 leucine-rich repeat transmembrane neuronal protein 4 isoform 2 precursor
NM_001347261.1 NP_001334190.1 leucine-rich repeat transmembrane neuronal protein 4 isoform 4 precursor
NM_178731.5 NP_848846.3 leucine-rich repeat transmembrane neuronal protein 4 isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables heparan sulfate proteoglycan binding IDA
IDA: 通过直接分析推断
23911104 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within AMPA glutamate receptor clustering IMP
IMP: 通过突变表型推断
23911104 MGI
acts upstream of or within neurotransmitter-gated ion channel clustering IDA
IDA: 通过直接分析推断
23911104 MGI
acts upstream of or within positive regulation of synapse assembly IDA
IDA: 通过直接分析推断
24613359 MGI
acts upstream of or within regulation of presynaptic membrane organization IDA
IDA: 通过直接分析推断
23911104 MGI
involved in regulation of synapse assembly IDA
IDA: 通过直接分析推断
23911103 MGI
involved in regulation of synapse assembly IMP
IMP: 通过突变表型推断
23911103 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of AMPA glutamate receptor complex IDA
IDA: 通过直接分析推断
22632720 MGI
is active in GABA-ergic synapse IDA
IDA: 通过直接分析推断
31974009 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
23911103 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
23911103 MGI
is active in photoreceptor ribbon synapse IDA
IDA: 通过直接分析推断
31974009 MGI
located in postsynaptic membrane IDA
IDA: 通过直接分析推断
23911104 MGI
is active in synapse IDA
IDA: 通过直接分析推断
31974009 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

leucine-rich repeat transmembrane neuronal protein 4

重组 Lrrtm4 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77069 LRRTM4 Protein, Mouse (HEK293, His) Q80XG9-1 (Q31-K424) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07844 LRRTM4 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lrrtm4 NCBI NCBI:80059
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