2. Gene
  3. Siglecg - sialic acid binding Ig-like lectin G Gene

Siglecg - sialic acid binding Ig-like lectin G Gene

  • 基因
  • 蛋白

种属: Mus musculus

同用名: Siglec-G; Siglec10; mSiglec-G; 9830164H23; A630096C01Rik

基因 ID: 243958 | 基因类型: protein coding

关于 Siglecg

功能概要

Predicted to enable SH2 domain binding activity; Phosphatase binding activity; and sialic acid binding activity. Involved in several processes, including negative regulation of calcium-mediated signaling; negative regulation of inflammatory response to wounding; and regulation of B cell proliferation. Acts upstream of or within hematopoietic progenitor cell differentiation. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in thymus primordium. Orthologous to several human genes including SIGLEC10 (sialic acid binding Ig like lectin 10). [provided by Alliance of Genome Resources, Apr 2022]

Siglecg 基因产物(2)

mRNA Protein Name
NM_001382486.1 NP_001369415.1 sialic acid-binding Ig-like lectin 10 isoform 2 precursor
NM_172900.4 NP_766488.2 sialic acid-binding Ig-like lectin 10 isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
19264983 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within hematopoietic progenitor cell differentiation IMP
IMP: 通过突变表型推断
24029230 MGI
involved in negative regulation of calcium-mediated signaling IGI
IGI: 通过遗传相互作用推断
20200274 MGI
involved in negative regulation of immunoglobulin production IGI
IGI: 通过遗传相互作用推断
20200274 MGI
involved in negative regulation of inflammatory response to wounding IPI
IPI: 通过物理相互作用推断
19264983 MGI
involved in regulation of B cell proliferation IGI
IGI: 通过遗传相互作用推断
20200274 MGI
involved in regulation of B cell proliferation IMP
IMP: 通过突变表型推断
20200274 MGI
involved in regulation of immune response IGI
IGI: 通过遗传相互作用推断
20200274 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

sialic acid-binding Ig-like lectin 10

sialic acid binding Ig-like lectin 10

siglec-10

Siglecg 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Siglec10 Q80ZE3 Rigi Mus musculus Q6Q899
Anti Tag CoIP
23374343
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 Siglecg 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70448 Siglec-10 Protein, Mouse (HEK293, Fc) Q80ZE3 (M19-K543) ≥95%
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