1. Gene
  2. Grm3 - glutamate metabotropic receptor 3 Gene

Grm3 - glutamate metabotropic receptor 3 Gene

中文名称:谷氨酸代谢型受体 3

种属: Rattus norvegicus

同用名: mGluR3

基因 ID: 24416 | 基因类型: protein coding

关于 Grm3

Primary_assembly 4: 24,365,115-24,609,804 forward strand.mRatBN7.2:CM026977.1

This gene has 3 transcripts (splice variants), 215 orthologues, 7 paralogues and is associated with 5 phenotypes. Restricted expression toward (RPKM 261.3).

功能概要

该基因编码的蛋白可启动第 II 组代谢型谷氨酸受体活性和支架蛋白结合活性。参与化学突触传递的调节。位于星形胶质细胞投射和轴突。与人类 GRM3(谷氨酸代谢受体 3)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables group II metabotropic glutamate receptor activity and scaffold protein binding activity. Involved in modulation of chemical synaptic transmission. Located in astrocyte projection and axon. Orthologous to human GRM3 (glutamate metabotropic receptor 3). [provided by Alliance of Genome Resources, Apr 2022]

Grm3 基因产物(1)

mRNA Protein Name
NM_001105712.1 NP_001099182.1 metabotropic glutamate receptor 3 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables group II metabotropic glutamate receptor activity IMP
IMP: 通过突变表型推断
12694929 RGD
enables scaffold protein binding IPI
IPI: 通过物理相互作用推断
28392297 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in modulation of chemical synaptic transmission IDA
IDA: 通过直接分析推断
12694929 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in astrocyte projection IDA
IDA: 通过直接分析推断
21753079 RGD
located in axon IDA
IDA: 通过直接分析推断
28392297 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

Grm3 蛋白结构

PBP1_mGluR_groupII

PBP1_mGluR_groupII: cd06375 (32 - 493)

NCD3G

NCD3G: pfam07562 (504 - 554)

7tmC_mGluR3

7tmC_mGluR3: cd15448 (574 - 827)

7tmC_mGluR3

7tmC_mGluR3: cd15448 (574 - 599)

7tmC_mGluR3

7tmC_mGluR3: cd15448 (611 - 632)

7tmC_mGluR3

7tmC_mGluR3: cd15448 (641 - 665)

7tmC_mGluR3

7tmC_mGluR3: cd15448 (687 - 707)

7tmC_mGluR3

7tmC_mGluR3: cd15448 (732 - 758)

7tmC_mGluR3

7tmC_mGluR3: cd15448 (766 - 789)

7tmC_mGluR3

7tmC_mGluR3: cd15448 (796 - 821)

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  • 903 a.a.
蛋白主名 其他名称

metabotropic glutamate receptor 3

glutamate receptor, metabotropic 3

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Grm3 NCBI NCBI:2913