Mtnr1b - melatonin receptor 1B Gene

中文名称：褪黑激素受体 1B

种属: Mus musculus

同用名: Mt2; Mel1b; Mel-1B-R

关于 Mtnr1b

功能概要

预测该基因编码的蛋白编码的蛋白可启动褪黑激素受体活性。预计参与多个过程，包括 cGMP 介导的信号传导的负调节；运输的负面监管；和调节神经冲动的传递。预计在昼夜节律的上游或之内起作用。预计是质膜的组成部分。预计在质膜上有活性。在中枢神经系统中表达；眼睛;直觉;和生殖系统。该基因的人类直系同源物与 2 型糖尿病有关。与人类 MTNR1B（褪黑激素受体 1B）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable Melatonin Receptor activity. Predicted to be involved in several processes, including negative regulation of cGMP-mediated signaling; negative regulation of transport; and regulation of transmission of nerve impulse. Predicted to act upstream of or within circadian rhythm. Predicted to be integral component of plasma membrane. Predicted to be active in plasma membrane. Is expressed in central nervous system; eye; gut; and reproductive system. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human MTNR1B (Melatonin Receptor 1B). [provided by Alliance of Genome Resources, Apr 2022]