2. Gene
  3. Junb - JunB proto-oncogene, AP-1 transcription factor subunit Gene

Junb - JunB proto-oncogene, AP-1 transcription factor subunit Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：Jun B 原癌基因，AP-1 转录因子亚基

种属: Rattus norvegicus

基因 ID: 24517 | 基因类型: protein coding

关于 Junb

功能概要

该基因编码的蛋白可启动 DNA 结合转录因子活性；双链 DNA 结合活性；和序列特异性 DNA 结合活性。参与多个过程，包括对 cAMP 的响应；对类固醇激素的反应；和 RNA 聚合酶 II 的转录。位于核内。肾癌的生物标志物。与人类 JUNB 同源（JunB 原癌基因，AP-1 转录因子亚基）。 [由基因组资源联盟提供，2022 年 4 月]

Enables DNA-binding transcription factor activity; double-stranded DNA binding activity; and sequence-specific DNA binding activity. Involved in several processes, including response to cAMP; response to steroid hormone; and transcription by RNA polymerase II. Located in nucleus. Biomarker of renal carcinoma. Orthologous to human JUNB (JunB proto-oncogene, AP-1 transcription factor subunit). [provided by Alliance of Genome Resources, Apr 2022]

Junb 基因产物(1)

mRNA Protein Name
NM_021836.2 NP_068608.2 transcription factor JunB
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
12371906 RGD
enables DNA-binding transcription factor activity IMP
IMP: 通过突变表型推断
10830307 RGD
enables double-stranded DNA binding IDA
IDA: 通过直接分析推断
10830307 RGD
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
10830307 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to hormone stimulus IEP
IEP: 通过表达模式推断
11460264 RGD
involved in cellular response to hypoxia IEP
IEP: 通过表达模式推断
8593588 RGD
involved in female pregnancy IEP
IEP: 通过表达模式推断
12080023 RGD
involved in response to 4-nitroquinoline N-oxide IEP
IEP: 通过表达模式推断
14674993 RGD
involved in response to cAMP IEP
IEP: 通过表达模式推断
18280640 RGD
involved in response to corticosterone IEP
IEP: 通过表达模式推断
18485334 RGD
involved in response to cytokine IEP
IEP: 通过表达模式推断
18280640 RGD
involved in response to light stimulus IEP
IEP: 通过表达模式推断
11146118 RGD
involved in response to mechanical stimulus IEP
IEP: 通过表达模式推断
15126239 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
10934195 RGD
involved in response to peptide hormone IEP
IEP: 通过表达模式推断
10934195 RGD
involved in response to progesterone IEP
IEP: 通过表达模式推断
12080023 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
12093589 RGD
involved in transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
10830307 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

Junb 蛋白结构

Jun

Jun: pfam03957 (5 - 252)

bZIP_Jun

bZIP_Jun: cd14696 (266 - 325)

bZIP_Jun

bZIP_Jun: cd14696 (267 - 318)

  • 0
  • 100
  • 200
  • 300
  • 344 a.a.
蛋白主名 其他名称

transcription factor JunB

Jun-B oncogene

jun B proto-oncogene

transcription factor AP-1 subunit JunB

transcription factor jun-B

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07057 JUNB Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS07058 Junb Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS07059 Junb Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Junb NCBI NCBI:3726
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