VGLL2 - vestigial like family member 2 Gene

中文名称：退化样家族成员 2

种属: Homo sapiens

同用名: VGL2; VITO1

基因 ID: 245806 | 基因类型: protein coding

关于 VGLL2

Cytogenetic location: 6q22.1 Genomic coordinates (GRCh38): 6:117,265,558-117,273,630 (from NCBI)

This gene has 2 transcripts (splice variants), 191 orthologues and 2 paralogues. Biased expression in heart (RPKM 1.5), prostate (RPKM 0.6) and 4 other tissues.

功能概要

该基因编码一种具有转录增强因子 1 (TEF-1) 相互作用结构域的蛋白质。编码的蛋白质可能在骨骼肌发育过程中充当 TEF-1 调节基因表达的辅助因子。已经观察到编码多种同种型的可变剪接转录物变体。[RefSeq 提供，2012 年 7 月]

This gene encodes a protein with a transcriptional enhancer factor 1 (TEF-1) interaction domain. The encoded protein may act as a co-factor of TEF-1 regulated gene expression during skeletal muscle development. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2012]

VGLL2 基因产物(2)

mRNA	Protein	Name
NM_153453.1	NP_703154.1	transcription cofactor vestigial-like protein 2 isoform 2
NM_182645.3	NP_872586.1	transcription cofactor vestigial-like protein 2 isoform 1

基因本体论

分子功能

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	25416956	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

VGLL2 蛋白结构

Vg_Tdu

0
100
200
317 a.a.

蛋白主名

其他名称

transcription cofactor vestigial-like protein 2

Vestigial and Tondu related protein 1

关联疾病

疾病名称

别名

Spindle Cell Rhabdomyosarcoma

Pleomorphic Rhabdomyosarcoma

Adult Pleomorphic Rhabdomyosarcoma	Anaplastic Rhabdomyosarcoma
Pleomorphic Rhabdomyosarcoma, Adult Type

Cellular Congenital Mesoblastic Nephroma

Progressive Relapsing Multiple Sclerosis

Prms	Progressive-Relapsing Ms
Multiple Sclerosis, Progressive Relapsing

Congenital Fibrosarcoma

Infantile Fibrosarcoma

Childhood Fibrosarcoma

Pediatric Fibrosarcoma

Lipofibromatosis-Like Neural Tumor

Smarca4-Deficient Sarcoma Of Thorax

Smarca4-Dts

Smarca4-Deficient Thoracic Sarcoma

Myofibroma

Lipoleiomyoma	Uterine Fibroids
Solitary Myofibromatosis	Myolipoma

Kidney Sarcoma

Renal Sarcoma

Sarcoma Of Kidney

Malignant Pineal Area Germ Cell Neoplasm

Pineal Germ Cell Tumor	Malignant Pineal Parenchymal Germ Cell Tumor
Pineal Region Germ Cell Tumor	Pineal Cell Tumor
Pineal Cell Tumour	Pineal Region Germinoma
Malignant Pineal Region Germ Cell Tumor	Pineal Germinoma

Kidney Clear Cell Sarcoma

Clear Cell Sarcoma Of Kidney	Childhood Kidney Clear Cell Sarcoma
Renal Clear Cell Sarcoma	Ccsk
Clear Cell Sarcoma Of The Kidney

Rhabdomyosarcoma

Embryonal Rhabdomyosarcoma

Rhabdomyosarcoma, Embryonal	Rhabdomyosarcoma Embryonal
Botryoid Rhabdomyosarcoma	Erms
Spindle Cell Rhabdomyosarcomas

Spindle Cell Sarcoma

Sarcoma	Sarcoma Spindle Cell
Sarcoma, Spindle Cell	Sarcoma - Category

Skeletal Muscle Cancer

Malignant Tumor Of Skeletal Muscle

Skeletal Muscle Neoplasm

Rhabdomyosarcoma 2

Alveolar Rhabdomyosarcoma	Rhabdomyosarcoma, Alveolar
Rhabdomyosarcoma Alveolar	RMS2
Rmsa	Rhabdomyosarcoma 2, Alveolar
Alveolar Childhood Rhabdomyosarcoma	Arms
Rhabdomyosarcoma, Type 2

Muscle Cancer

Myosarcoma	Malignant Neoplasm Of Muscle
Malignant Tumor Of Muscle	Malignant Tumor Of The Muscle
Muscle Neoplasms	Myomatous Neoplasm

Craniometaphyseal Dysplasia, Autosomal Dominant

Craniometaphyseal Dysplasia	CMDD
Cmdj	Cmd
Autosomal Dominant Craniometaphyseal Dysplasia	Craniometaphyseal Dysplasia, Jackson Type
Craniometaphyseal Dysplasia Jackson Type	Autosomal Recessive Craniometaphyseal Dysplasia
Cmdr	Dysplasia, Craniometaphyseal, Autosomal Dominant
Craniometaphyseal Dysplasia, Autosomal Recessive Type

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS15645	VGLL2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Felis catus	VGLL2	VGNC	VGNC:102546
Mus musculus	VGLL2	MGD	MGI:2447460
Macaca mulatta	VGLL2	VGNC	VGNC:79237
Canis familiaris	VGLL2	VGNC	VGNC:48258
Rattus norvegicus	VGLL2	RGD	RGD:1311903
Bos taurus	VGLL2	VGNC	VGNC:36791

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

VGLL2 - vestigial like family member 2 Gene

关于 VGLL2

功能概要

VGLL2 基因产物(2)

VGLL2 蛋白结构

关联疾病

直系同源

热门区域

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VGLL2 - vestigial like family member 2 Gene

关于 VGLL2

功能概要

VGLL2 基因产物(2)

VGLL2 蛋白结构

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z