1. Gene
  2. CTAG1A - cancer/testis antigen 1A Gene

CTAG1A - cancer/testis antigen 1A Gene

中文名称:癌症/睾丸抗原 1A

种属: Homo sapiens

同用名: ESO1; CT6.1; LAGE-2; LAGE2A; NY-ESO-1

基因 ID: 246100 | 基因类型: protein coding

关于 CTAG1A

Cytogenetic location: Xq28 Genomic coordinates (GRCh38): X:154,585,133-154,586,816 (from NCBI)

This gene has 2 transcripts (splice variants), 171 orthologues and 3 paralogues. Restricted expression toward testis (RPKM 4.4).

功能概要

该基因编码的蛋白质是一种存在于各种类型癌症中的肿瘤细胞抗原,这使其成为癌症疫苗的良好候选者。该基因在正常卵巢和睾丸组织中也有高表达。在同一条染色体上发现了该基因的相同副本。[RefSeq 提供,2015 年 12 月]

The protein encoded by this gene is a tumor cell antigen found in various types of cancers, which makes it a good candidate for a Cancer vaccine. This gene is also highly expressed in normal ovary and testis tissues. An identical copy of this gene is found on the same chromosome. [provided by RefSeq, Dec 2015]

CTAG1A 基因产物(1)

mRNA Protein Name
NM_139250.2 NP_640343.1 cancer/testis antigen 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
17137291 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

cancer/testis antigen 1

New York Esophageal Squamous Cell Carcinoma 1

关联疾病

疾病名称 别名
Synovium Cancer

Malignant Tumor Of Synovium

Synovial Neoplasm

Cellular Myxoid Liposarcoma

Round Cell Liposarcoma

Subclavian Steal Syndrome

Subclavian Artery Stenosis

Subclavian Steal Phenomenon

Subclavian Steal Steno-Occlusive Disease

Subclavian Steal

Myxoid Liposarcoma

Myxoid/Round Cell Liposarcoma

Liposarcoma, Myxoid

Mrcls

Myxoliposarcoma

MXLIPO

Liposarcoma Myxoid

Liposarcoma

Sarcoma, Synovial

Synovial Sarcoma

Synovialosarcoma

Synovial Cell Sarcoma

Sarcoma Synovial

Epithelioid Cell Synovial Sarcoma

Synovial Sarcoma, Epithelioid Cell

Epithelioid Synovial Sarcoma

Dedifferentiated Liposarcoma

Ddls

Liposarcoma Dedifferentiated

Liposarcoma, Dedifferentiated

Small Intestine Leiomyosarcoma

Leiomyosarcoma Of The Small Bowel

Smooth Muscle Connective Tissue Tumor

Leiomyosarcoma Of Small Intestine

Esophageal Cancer

Esophageal Carcinoma

Carcinoma Of Esophagus

Esophageal Squamous Cell Carcinoma, Somatic

Esophageal Carcinoma, Somatic

Esophagus Cancer

Gastric Cardia Adenocarcinoma

Esophageal Neoplasms

Esophageal Cancer, Somatic

Cancer Of Esophagus

Cancer Of Oesophagus

Carcinoma Of Oesophagus

Ca Lower Third Oesophagus

Ca Middle Third Oesophagus

Malignant Neoplasm Of Distal Third Of Esophagus

Malignant Neoplasm Of Lower Third Of Oesophagus

Malignant Neoplasm Of Middle Third Of Oesophagus

Malignant Neoplasm Of Proximal Third Of Esophagus

Malignant Neoplasm Of Upper Third Esophagus

Malignant Tumor Of Abdominal Esophagus

Malignant Tumor Of Distal Third Of Esophagus

Malignant Tumor Of Proximal Third Of Esophagus

Malignant Tumor Of The Middle Third Of The Esophagus

ESCR

Aerodigestive Tract Cancer

Escc

Esophageal Squamous Cell Carcinoma

Cancer, Esophageal

Malignant Neoplasm Of Esophagus

Squamous Cell Carcinoma Of Esophagus

Malignant Neoplasm Of Middle Third Of Esophagus

Wilms Tumor 1

Nephroblastoma

Wilms Tumor

WT1

Wilms' Tumor

Bilateral Wilms Tumor

Wilms Tumor, Type 1

Wilms Tumor, Somatic

Adult Nephroblastoma

Wt1 Disorder

Renal Embryonic Tumor

Adult Kidney Wilms Tumor

Childhood Kidney Wilms Tumor

Nonanaplastic Kidney Wilms Tumor

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus CTAG1A MGD MGI:3644285