2. Gene
  3. Nrp1 - neuropilin 1 Gene

Nrp1 - neuropilin 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Nrp

基因 ID: 246331 | 基因类型: protein coding

关于 Nrp1

功能概要

Enables semaphorin receptor activity. Involved in negative regulation of axon extension involved in axon guidance and response to wounding. Located in cell surface; growth cone; and neuronal cell body. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human NRP1 (neuropilin 1). [provided by Alliance of Genome Resources, Apr 2022]

Nrp1 基因产物(1)

mRNA Protein Name
NM_145098.2 NP_659566.1 neuropilin-1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
9288754 RGD
enables semaphorin receptor activity IMP
IMP: 通过突变表型推断
9288754 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of axon extension involved in axon guidance IMP
IMP: 通过突变表型推断
9288754 RGD
involved in positive regulation of platelet-derived growth factor receptor signaling pathway IMP
IMP: 通过突变表型推断
26410366 RGD
involved in positive regulation of smooth muscle cell chemotaxis IMP
IMP: 通过突变表型推断
26410366 RGD
involved in positive regulation of vascular associated smooth muscle cell migration IMP
IMP: 通过突变表型推断
26410366 RGD
involved in wound healing IMP
IMP: 通过突变表型推断
26410366 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
9288754 RGD
located in cell surface IDA
IDA: 通过直接分析推断
9288754 RGD
located in growth cone IDA
IDA: 通过直接分析推断
9288754 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
9288754 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

neuropilin-1

vascular endothelial cell growth factor 165 receptor

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P3448 Certepetide Activator 99.40% Phase 2
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P99386 Vesencumab Inhibitor ≥99.0% Phase 1
Pre-clinical Phase
生物活性分子 (12)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-10799 EG00229 trifluoroacetate Antagonist 98.18% 否
HY-112151A EG01377 dihydrochloride Inhibitor 98.98% 否
HY-P1663A ATWLPPR Peptide TFA Inhibitor 99.81% 否
HY-133034 NRP1 antagonist 1 Antagonist 99.80% 否
HY-147762 NRP1 antagonist 2 Antagonist 99.05% 否
HY-RS09579 NRP1 Human Pre-designed siRNA Set A / 否
HY-112151 EG01377 Inhibitor / 否
HY-163062 Tubulin/NRP1-IN-1 / 否
HY-P10097 Flt2₋11 Inhibitor / 否
HY-P10787 tLyP-1 peptide Inhibitor / 否
HY-P10788 CK3 peptide Inhibitor / 否
HY-128446 CAY10781 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nrp1 NCBI NCBI:8829
Macaca fascicularis Nrp1 NCBI NCBI:102145235
Mus musculus Nrp1 NCBI NCBI:18186
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