Ren - renin Gene

中文名称：肾素

种属: Rattus norvegicus

同用名: Ren1; RENAA; RATRENAA

关于 Ren

功能概要

该基因编码的蛋白可启动内肽酶活性和胰岛素样生长因子受体结合活性。参与多个过程，包括肽代谢过程；对脂多糖的反应；以及对含嘌呤化合物的反应。位于细胞质和细胞外空间。用于研究高血压。原发性胆汁性胆管炎的生物标志物。该基因的人类直系同源物与原发性高血压有关；家族性青少年高尿酸血症性肾病；手足口病；高血压;和门静脉高压症。与人类 REN（肾素）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables endopeptidase activity and insulin-like growth factor receptor binding activity. Involved in several processes, including peptide metabolic process; response to lipopolysaccharide; and response to purine-containing compound. Located in cytoplasm and extracellular space. Used to study hypertension. Biomarker of primary biliary cholangitis. Human ortholog(s) of this gene implicated in essential hypertension; familial juvenile hyperuricemic nephropathy; hand, foot and mouth disease; hypertension; and portal hypertension. Orthologous to human REN (Renin). [provided by Alliance of Genome Resources, Apr 2022]