2. Gene
  3. Adrb1 - adrenoceptor beta 1 Gene

Adrb1 - adrenoceptor beta 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: B1AR; RATB1AR

基因 ID: 24925 | 基因类型: protein coding

关于 Adrb1

功能概要

Enables amine binding activity and beta1-adrenergic receptor activity. Involved in several processes, including positive regulation of transport; regulation of heart contraction; and regulation of muscle system process. Located in cytoplasm; nucleus; and plasma membrane. Used to study congestive heart failure; dilated cardiomyopathy; myocardial infarction; periodontitis; and renovascular hypertension. Biomarker of hyperglycemia; hypertension; and type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including chronic obstructive pulmonary disease; hypertension (multiple); low tension glaucoma; obstructive sleep apnea; and periodontitis. Orthologous to human ADRB1 (adrenoceptor beta 1). [provided by Alliance of Genome Resources, Apr 2022]

Adrb1 基因产物(1)

mRNA Protein Name
NM_012701.2 NP_036833.2 beta-1 adrenergic receptor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables amine binding IPI
IPI: 通过物理相互作用推断
6289140 RGD
enables beta1-adrenergic receptor activity IDA
IDA: 通过直接分析推断
12514203 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
16316992 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
12514203 RGD
involved in Rho protein signal transduction IMP
IMP: 通过突变表型推断
18306009 RGD
involved in glycogen catabolic process IDA
IDA: 通过直接分析推断
17911346 RGD
involved in inhibitory postsynaptic potential IMP
IMP: 通过突变表型推断
18262504 RGD
involved in lipid homeostasis IMP
IMP: 通过突变表型推断
22457517 RGD
involved in memory IMP
IMP: 通过突变表型推断
17961922 RGD
involved in negative regulation of smooth muscle contraction IMP
IMP: 通过突变表型推断
18306009 RGD
involved in negative regulation of urine volume IDA
IDA: 通过直接分析推断
7912752 RGD
involved in positive regulation of adenylate cyclase activity IMP
IMP: 通过突变表型推断
21143600 RGD
involved in positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway IMP
IMP: 通过突变表型推断
18202135 RGD
involved in positive regulation of apoptotic process IMP
IMP: 通过突变表型推断
17143192 RGD
involved in positive regulation of calcium ion import across plasma membrane IDA
IDA: 通过直接分析推断
11408541 RGD
involved in positive regulation of cation channel activity IDA
IDA: 通过直接分析推断
22505670 RGD
involved in positive regulation of cell growth involved in cardiac muscle cell development IMP
IMP: 通过突变表型推断
18194989 RGD
involved in positive regulation of heart rate IMP
IMP: 通过突变表型推断
9089896 RGD
involved in positive regulation of long-term synaptic potentiation IDA
IDA: 通过直接分析推断
21848869 RGD
involved in positive regulation of systemic arterial blood pressure IMP
IMP: 通过突变表型推断
18931026 RGD
involved in positive regulation of the force of heart contraction by norepinephrine IDA
IDA: 通过直接分析推断
19133992 RGD
involved in protein localization to organelle IDA
IDA: 通过直接分析推断
22105697 RGD
involved in regulation of calcium ion transport IDA
IDA: 通过直接分析推断
19133992 RGD
involved in regulation of cardiac muscle cell contraction IDA
IDA: 通过直接分析推断
19525381 RGD
involved in regulation of cardiac muscle cell contraction IMP
IMP: 通过突变表型推断
22216755 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in plasma membrane IDA
IDA: 通过直接分析推断
12391161 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

beta-1 adrenergic receptor

adrenergic receptor, beta 1

adrenergic, beta-1-, receptor

beta 1-adrenergic receptor beta 1-AR

beta-1 adrenoceptor

beta-1 adrenoreceptor

Adrb1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Adrb1 P18090 Magi3 Rattus norvegicus Q9JK71
Anti Bait CoIP
16316992
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00414 ADRB1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Adrb1 NCBI NCBI:153
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