2. Gene
  3. Slc16a1 - solute carrier family 16 member 1 Gene

Slc16a1 - solute carrier family 16 member 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：溶质载体家族 16 成员 1

种属: Rattus norvegicus

同用名: MCT1; RNMCT1; RATMCT1

基因 ID: 25027 | 基因类型: protein coding

关于 Slc16a1

Primary_assembly 2: 192,124,289-192,144,611 forward strand.mRatBN7.2:CM026975.1

This gene has 2 transcripts (splice variants), 339 orthologues, 13 paralogues and is associated with 8 phenotypes. Biased expression in Heart (RPKM 11.1), Thymus (RPKM 589.2) and 9 other tissues.

功能概要

实现相同的蛋白质结合活性；单羧酸跨膜转运蛋白活性；和有机环状化合物结合活性。参与细胞对有机环状化合物和质膜乳酸转运的反应。位于顶端质膜和基底外侧质膜。是质膜的组成部分。该基因的人类直系同源物与家族性高胰岛素血症性低血糖症 7 相关。与人类 SLC16A1（溶质载体家族 16 成员 1）直系同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables identical protein binding activity; monocarboxylic acid transmembrane transporter activity; and organic cyclic compound binding activity. Involved in cellular response to organic cyclic compound and plasma membrane lactate transport. Located in apical plasma membrane and basolateral plasma membrane. Is integral component of plasma membrane. Human ortholog(s) of this gene implicated in familial hyperinsulinemic hypoglycemia 7. Orthologous to human SLC16A1 (solute carrier family 16 member 1). [provided by Alliance of Genome Resources, Apr 2022]

Slc16a1 基因产物(1)

mRNA Protein Name
NM_012716.2 NP_036848.1 monocarboxylate transporter 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables carboxylic acid transmembrane transporter activity IMP
IMP: 通过突变表型推断
10714609 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
19473976 RGD
enables lactate:proton symporter activity IDA
IDA: 通过直接分析推断
9639576 RGD
enables monocarboxylic acid transmembrane transporter activity IDA
IDA: 通过直接分析推断
8526936 RGD
enables organic cyclic compound binding IMP
IMP: 通过突变表型推断
19473976 RGD
enables organic cyclic compound binding IPI
IPI: 通过物理相互作用推断
19473976 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
11719518 RGD
enables solute:proton symporter activity IDA
IDA: 通过直接分析推断
9374487 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in carboxylic acid transmembrane transport IMP
IMP: 通过突变表型推断
10714609 RGD
involved in cellular response to organic cyclic compound IEP
IEP: 通过表达模式推断
19473976 RGD
involved in cellular response to organic cyclic compound IMP
IMP: 通过突变表型推断
19473976 RGD
involved in lactate transmembrane transport IDA
IDA: 通过直接分析推断
19473976 RGD
involved in lactate transmembrane transport IMP
IMP: 通过突变表型推断
19473976 RGD
involved in monocarboxylic acid transport IDA
IDA: 通过直接分析推断
8526936 RGD
involved in plasma membrane lactate transport IDA
IDA: 通过直接分析推断
19929853 RGD
involved in plasma membrane lactate transport IMP
IMP: 通过突变表型推断
17127621 RGD
involved in pyruvate transmembrane transport IDA
IDA: 通过直接分析推断
9639576 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
18619525 RGD
located in basolateral plasma membrane IDA
IDA: 通过直接分析推断
10564700 RGD
located in plasma membrane IDA
IDA: 通过直接分析推断
11719518 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

Slc16a1 蛋白结构

2A0113

2A0113: TIGR00892 (0 - 461)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 494 a.a.
蛋白主名 其他名称

monocarboxylate transporter 1

MCT 1

solute carrier 16 (monocarboxylic acid transporter), member 1

solute carrier family 16 (monocarboxylate transporter), member 1

solute carrier family 16 (monocarboxylic acid transporters), member 1

solute carrier family 16, member 1 (monocarboxylic acid transporter 1)

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13016 SLC16A1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS13017 Slc16a1 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS13018 Slc16a1 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Slc16a1 NCBI NCBI:6566
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