Avpr2 - arginine vasopressin receptor 2 Gene

中文名称：精氨酸加压素受体 2

种属: Rattus norvegicus

关于 Avpr2

功能概要

预测该基因编码的蛋白可启动肽结合活性和加压素受体活性。参与多个过程，包括肾钠排泄的负调节；尿量的负调节；和全身动脉血压的正调节。预测定位于细胞质囊泡；细胞质的核周区；和质膜。预计是质膜的组成部分。用于研究高血压。输尿管梗阻的生物标志物。该基因的人类直系同源物与肾源性尿崩症和不适当抗利尿的肾源性综合征有关。与人类 AVPR2（精氨酸加压素受体 2）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable peptide binding activity and Vasopressin Receptor activity. Involved in several processes, including negative regulation of renal sodium excretion; negative regulation of urine volume; and positive regulation of systemic arterial blood pressure. Predicted to be located in cytoplasmic vesicle; perinuclear region of cytoplasm; and plasma membrane. Predicted to be integral component of plasma membrane. Used to study hypertension. Biomarker of ureteral obstruction. Human ortholog(s) of this gene implicated in nephrogenic diabetes insipidus and nephrogenic syndrome of inappropriate antidiuresis. Orthologous to human AVPR2 (arginine Vasopressin Receptor 2). [provided by Alliance of Genome Resources, Apr 2022]