1. Gene
  2. Chrm1 - cholinergic receptor, muscarinic 1 Gene

Chrm1 - cholinergic receptor, muscarinic 1 Gene

种属: Rattus norvegicus

基因 ID: 25229 | 基因类型: protein coding

关于 Chrm1

功能概要

Enables G protein-coupled acetylcholine receptor activity. Involved in G protein-coupled acetylcholine receptor signaling pathway; neuromuscular synaptic transmission; and positive regulation of intracellular protein transport. Located in several cellular components, including axon terminus; dendrite; and postsynaptic density. Is active in glutamatergic synapse. Is integral component of postsynaptic density membrane and integral component of presynaptic membrane. Human ortholog(s) of this gene implicated in Lambert-Eaton myasthenic syndrome; asthma; and myasthenia gravis. Orthologous to human CHRM1 (cholinergic receptor muscarinic 1). [provided by Alliance of Genome Resources, Apr 2022]

Chrm1 基因产物(1)

mRNA Protein Name
NM_080773.2 NP_542951.1 muscarinic acetylcholine receptor M1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G protein-coupled acetylcholine receptor activity IDA
IDA: 通过直接分析推断
12534975 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in G protein-coupled acetylcholine receptor signaling pathway IDA
IDA: 通过直接分析推断
12534975 RGD
involved in neuromuscular synaptic transmission IDA
IDA: 通过直接分析推断
12534975 RGD
involved in positive regulation of intracellular protein transport IDA
IDA: 通过直接分析推断
17908240 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in asymmetric synapse IDA
IDA: 通过直接分析推断
8182478 RGD
located in axon terminus IDA
IDA: 通过直接分析推断
8182478 RGD
located in dendrite IDA
IDA: 通过直接分析推断
8182478 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
8182478 RGD
is active in postsynaptic density membrane IDA
IDA: 通过直接分析推断
8182478 RGD
is active in presynaptic membrane IDA
IDA: 通过直接分析推断
8182478 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

muscarinic acetylcholine receptor M1

Cholinergic receptor, muscarin 1

m1 muscarinic acetylcholine receptor protein

重组 Chrm1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72138 CHRM1 Protein, Rat (His) P08482 (R210-T366) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Chrm1 NCBI NCBI:1128
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