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  2. Cdk11b - cyclin-dependent kinase 11B Gene

Cdk11b - cyclin-dependent kinase 11B Gene

中文名称:细胞周期蛋白依赖性激酶 11B

种属: Rattus norvegicus

同用名: Cdk11; Cdc2l1

基因 ID: 252879 | 基因类型: protein coding

关于 Cdk11b

Primary_assembly 5: 166,212,829-166,238,876 forward strand.mRatBN7.2:CM026978.1

This gene has 2 transcripts (splice variants), 203 orthologues, 24 paralogues and is associated with 13 phenotypes. Biased expression in Thymus (RPKM 8.7), Spleen (RPKM 77.3) and 9 other tissues.

功能概要

预计该基因编码的蛋白可启动 ATP 结合活性和细胞周期蛋白依赖性蛋白丝氨酸/苏氨酸激酶活性。预计参与多个过程,包括蛋白质磷酸化;调节细胞生长;和 mRNA 加工的调节。预计在胚泡发育的上游或内部发挥作用;凋亡信号通路的负调控;和有丝分裂核分裂的调节。预测位于细胞核膜和细胞质的核周区。预计活跃于核心。与几个人类基因同源,包括 CDK11B(细胞周期蛋白依赖性激酶 11B)。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable ATP binding activity and cyclin-dependent protein serine/threonine kinase activity. Predicted to be involved in several processes, including protein phosphorylation; regulation of cell growth; and regulation of mRNA processing. Predicted to act upstream of or within blastocyst development; negative regulation of apoptotic signaling pathway; and regulation of mitotic nuclear division. Predicted to be located in nuclear membrane and perinuclear region of cytoplasm. Predicted to be active in nucleus. Orthologous to several human genes including CDK11B (cyclin dependent kinase 11B). [provided by Alliance of Genome Resources, Apr 2022]

Cdk11b 基因产物(1)

mRNA Protein Name
NM_145766.2 NP_665709.2 cyclin-dependent kinase 11B

Cdk11b 蛋白结构

STKc_CDC2L1

STKc_CDC2L1: cd07843 (420 - 711)

  • 0
  • 200
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  • 600
  • 784 a.a.
蛋白主名 其他名称

cyclin-dependent kinase 11B

PITSLRE serine/threonine-protein kinase CDC2L1

cell division cycle 2 homolog-like 1

cell division cycle 2-like protein kinase 1

cell division protein kinase 11

cyclin-dependent kinase 11

galactosyltransferase-associated protein kinase p58/GTA

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cdk11b NCBI NCBI:984