1. Gene
  2. Cyp7b1 - cytochrome P450 family 7 subfamily B member 1 Gene

Cyp7b1 - cytochrome P450 family 7 subfamily B member 1 Gene

种属: Rattus norvegicus

基因 ID: 25429 | 基因类型: protein coding

关于 Cyp7b1

功能概要

Predicted to enable oxysterol 7-alpha-hydroxylase activity. Involved in several processes, including circadian rhythm; memory; and response to cAMP. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in congenital bile acid synthesis defect 3 and hereditary spastic paraplegia 5A. Orthologous to human CYP7B1 (Cytochrome P450 family 7 subfamily B member 1). [provided by Alliance of Genome Resources, Apr 2022]

Cyp7b1 基因产物(1)

mRNA Protein Name
NM_019138.1 NP_062011.1 25-hydroxycholesterol 7-alpha-hydroxylase
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in circadian rhythm IDA
IDA: 通过直接分析推断
12759897 RGD
involved in memory IDA
IDA: 通过直接分析推断
17065445 RGD
involved in response to cAMP IEP
IEP: 通过表达模式推断
12029625 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
12029625 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

25-hydroxycholesterol 7-alpha-hydroxylase

HCT-1

cytochrome P450 7B1

cytochrome P450, family 7, subfamily b, polypeptide 1

cytochrome P450, subfamily 7B, polypeptide 1

hippocampal transcript 1 protein

oxysterol 7-alpha-hydroxylase

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cyp7b1 NCBI NCBI:9420